As to the OP, here's how it will go.
The media will focus on what she wears, how she looks, how she interacts with other men, how she interacts with other women, but most comparisons will be gender based.
Repub male politicians, the vile ones in particular, will not be able to keep their mouths shut. We will hear even more appalling garbage spewed. It will bring out the worst in them.
At the state level, even more will be incensed that a woman is in the White House. They will 'show us' by carrying out even more draconian anti-woman legislation.
Among the people, if she's thin & pretty, a lot of men will dismiss her authority but say how much they would like to fuck her. If she's not thin, a lot of men will dismiss her authority and call her a cow & that's the kindest thing they will say. Most of these men are repubs, but we have them in our party, too.
For young women & girls, it will be good, a ceiling broken. It will always be a struggle, but there is always, "If someone else did it, I can too." I know a woman who makes six figures selling Mary Kay & that is her mantra. 
on edit: I would never vote for someone based on gender.
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