Three people with inherited diseases successfully treated with CRISPR

[Judi Lynn]

HEALTH 12 June 2020
By Michael Le Page



Sickle cell disease can distort red blood cells
Stocktrek Images, Inc/Alamy

Two people with beta thalassaemia and one with sickle cell disease no longer require blood transfusions, which are normally used to treat severe forms of these inherited diseases, after their bone marrow stem cells were gene-edited with CRISPR.

Result of the ongoing trial, which is the first to use CRISPR to treat inherited genetic disorders, were announced today at a virtual meeting of the European Hematology Association.

“The preliminary results… demonstrate, in essence, a functional cure for patients with beta thalassaemia and sickle cell disease,” team member Haydar Frangoul at Sarah Cannon Research Institute in Nashville, Tennessee, said in a statement.

Beta thalassaemia and sickle cell are diseases caused by mutations that affect haemoglobin, the protein that carries oxygen in red blood cells. Those with severe forms require regular blood transfusions.

More:
https://www.newscientist.com/article/2246020-three-people-with-inherited-diseases-successfully-treated-with-crispr/#ixzz6PQmc13zD

[Cicada]

1. Homo Sapiens will soon be replaced by Homo Crsper

I’m serious.

I see a cure for fat, ugly, old so I recommend investing in urban prime disco properties.


And selling nursing home stocks short.

We may Pretty much cure natural death. I’m serious about that too.

[DarleenMB]

3. Nature doesn't work that way.

The Newtonian model of physics is completely wrong when it comes to the human body (among other things). Quantum reality shows us that EVERYthing is interconnected and fiddling with one part can wreak havoc right down the line.

Let's wait and see what happens to these three people in a year or so.

[Cicada]

4. Think 100 years from now

Doctors may find a cure for Republicanism

[Roland99]

2. Paging Dr. McCoy. Paging Dr. McCoy

[progressoid]

5. So...we approve of genetic modification now?