Researchers Develop Stem Cells That Attack and Destroy HIV
Source: Raw Story / PLos Pathogens
Researchers develop stem cells that attack and destroy HIV
By Andrew Jones
Monday, April 16, 2012 10:55 EDT Scientists from the University of California Los Angeles have found that genetically engineered human stem cells can suppress HIV in living mice, raising the hope for a breakthrough cure for HIV patients.
In a recent study from the journal PLoS Pathogens, researchers wanted to go further than previous studies that used vaccines to slow HIV progression. They cloned a molecule that controls killer T cells, white blood cells that recognize and kill HIV-infected cells. The molecule was then injected with human blood stem cells inside of mice to control those cells for observation.
Over a month after injecting the cells into the mice, researchers found an increase in the amount of T-cells needed to fight HIV cells. The study revealed for the first time that engineered cells were capable of developing and migrating to the organs to fight infection there. Lead researcher Scott G. Kitchen, an assistant professor at UCLAs David Geffen School of Medicine, was pleased with the results.
We believe that this study lays the groundwork for the potential use of this type of an approach in combating HIV infection in infected individuals, in hopes of eradicating the virus from the body, Kitchen said. We believe that this is the first step in developing a more aggressive approach in correcting the defects in the human T cell responses that allow HIV to persist in infected people.
Read more: http://www.rawstory.com/rs/2012/04/16/researchers-develop-stem-cells-that-attack-and-destroy-hiv
cindyperry2010
(846 posts)closeupready
(29,503 posts)there seems to be so much progress lately being achieved in the search for one, it can only lead to better life expectancy and quality of life for those with HIV.
Lawlbringer
(550 posts)But I can't help but feel like this is going to get buried deep by the bureaucrats.
Either that or it'll lead to the Zombie Apocalypse.
ZombieHorde
(29,047 posts)iandhr
(6,852 posts)rfranklin
(13,200 posts)Every stem cell is sacred!
Igel
(35,317 posts)The kind of stem cells in your body that produces all the different kinds of blood cells. HSCs, hemotopoietic stem cells.
They tested it on "humanized mice" with a variety of fetal tissues, but the genetic manipulation happened on (the ambiguously named) adult stem cells.
Few fundies have a problem with these. In fact, they're what fundies keep claiming show more promise than human embryonic stem cells, HESCs.
Sometimes snark is ironic.
rfranklin
(13,200 posts)it hurts my head and drowns out the voice of Jesus in my head.
originalpckelly
(24,382 posts)where it will be cured in at most 20 years, or there will be a treatment so good people can live with it without even having major side effects, like some of the current drugs have.