Coronavirus May Have Spread in U.S. for Weeks, Gene Sequencing Suggests
Source: NYT
By Sheri Fink and Mike Baker
March 1, 2020
Updated 1:55 p.m. ET
Researchers who have examined the genomes of two coronavirus infections in Washington State say the similarities between the cases suggest that the virus may have been spreading in the state for weeks.
Washington had the United States first confirmed case of coronavirus, announced by the C.D.C. on Jan. 20. Based on an analysis of the viruss genetic sequence, another case that surfaced in the state and was announced on Friday probably was descended from that first case.
The two people live in the same county, but are not known to have had contact with one another, and the second case occurred well after the first would no longer be expected to be contagious. So the genetic findings suggest that the virus has been spreading through other people in the community for close to six weeks, according to one of the scientists who compared the sequences, Trevor Bedford, an associate professor at the Fred Hutchinson Cancer Research Center and the University of Washington.
Dr. Bedford said it was possible that the two cases could be unrelated, and had been introduced separately into the United States. But he said that was unlikely, however, because in both cases the virus contained a genetic variation that appears to be rare it was found in only two of the 59 samples whose sequences have been shared from China, where the virus originated.
Read more: https://www.nytimes.com/2020/03/01/health/coronavirus-washington-spread.html
Iliyah
(25,111 posts)Canoe52
(2,949 posts)hlthe2b
(102,326 posts)DENVERPOPS
(8,843 posts)trying to explain DNA to a pre-schooler........
gibraltar72
(7,508 posts)The window opened some time ago to head this off. We weren't prepared and did virtually nothing. Here we are.
Igel
(35,332 posts)Or take the measures necessary to contain it. Those two sentences could mean anything, so I'll elaborate.
With the first word of a virus that can spread so easily while no symptoms are present there should have been lockdown. That guy getting off the plane? Might have sat next to somebody who gave it to him, but who himself doesn't know he's contracted the "illness" and won't for another week.
By the time the guy in the next seat over comes sick and they have to track down who he infected, *that* person is infectious and might have infected dozens of people.
And since that was occurring since *before* the first reported case, you'd have to be able to track everybody backwards in time for two, 4, 6, 8 weeks. Test them. And everybody they came into contact with, and those they contacted, and those *they* contacted. May as well shut down everything at that point. It might have been circulating in the US even before it was first reported in any noticeable way in China, and before it was determined it could be transferred by asymptomatic carriers. You don't check for things you don't suspect.
That's the level of competence we needed. Anything less is merely human incompetence. Then we're arguing about levels of competence, and that becomes a discussion of "how long did we drag out the process?" That's what's important: How long it takes for most to get infected. That determines the supplies required, hospital bed need, whether there'll be a vaccine in time, whether we find good palliative measures.
Those who screwed up screwed up massively *before* the first bit of politicking began, and the most serious screw ups (by which I mean "normal human behavior that doesn't involve precognition and omniscience" happened in China. Weeks before the Congressionally increased CDC budget became a much-publicized decrease, for instance (although community preparedness funds were cut, it's still not like all government spending is necessarily just federal and just from the CDC--that's butt-covering excuse of an accusation).
G_j
(40,367 posts)for a bunch of do-nothings
GeorgeGist
(25,322 posts)may have been spreading in the state to may have spread in the U.S.
Dennis Donovan
(18,770 posts)Mr.Bill
(24,311 posts)with recirculated air and common restrooms.
Pacifist Patriot
(24,653 posts)it's spreading in the US. I'd be shocked if it wasn't already in the majority of US states if not all of them.
Warpy
(111,305 posts)and probably a few days before they feel ill. That's why containment is not going to work, that window has shut tight. People who were shedding virus traveled worldwide from China for at least a week before anybody knew anything, here or there. The virus persists on surfaces after it dries out.
Good handwashing is going to be key here, along with not touching your face with your fingers. We probably can't eliminate exposure, we can only reduce it.
JudyM
(29,251 posts)Warpy
(111,305 posts)and eating good food, not too much, mostly plants. Get adequate sleep. If you smoke, stop.
You know, the boring stuff that doesn't involve slamming down handsful of vitamins.
JudyM
(29,251 posts)well as a few other supplements listed here:
https://www.elsevier.com/about/press-releases/research-and-journals/recent-research-points-the-way-toward-a-practical-nutraceutical-strategy-for-coping-with-rna-virus-infections-including-influenza-and-coronavirus
Heres what CDC has to say about prevention, not as detailed. https://www.cdc.gov/coronavirus/2019-ncov/community/index.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fpreparing-individuals-communities.html
Captain Zero
(6,821 posts)And some Black currant supposedly good for inflammation.
HockeyMom
(14,337 posts)This also happens with the flu as well. There are people who never show any symptoms of being infected with the flu.
paleotn
(17,937 posts)bucolic_frolic
(43,244 posts)that the Rhode Island case visited Italy mid-February. So 1-2 weeks. This is going to explode.
JudyM
(29,251 posts)contact, either.
Hoping...
Evolve Dammit
(16,750 posts)have no idea. How could you?
LiberalArkie
(15,724 posts)Evolve Dammit
(16,750 posts)wishstar
(5,271 posts)Italy in just the last 2 days jumped from 900 cases to almost 1400 cases with deaths going up from 20 to 34
Evolve Dammit
(16,750 posts)mommymarine2003
(261 posts)As a transplanted Washingtonian now living in the Portland, OR area, my husband and I drove up for the weekend for our grandson's 6th birthday. Having just had the first case of the virus in Oregon announced on Friday, we had quite a discussion at lunch in Tukwila about what we need to do to prepare for the probable pandemic. My youngest child works for the Seattle Fire Department, and he discussed how they are preparing for this. My son-in-law works in a care facility, so that is worrisome for him. Meanwhile, stores up there are having a rush on toilet paper, bottled water, hand sanitizer, and soap. It reminded me of when Mt. St. Helens erupted for the second time. I lived in Eastern Washington, and everyone rushed to the stores to stock up. All the bread, milk, etc. was gone.
The unknown is pretty scary, but at least Oregon and Washington have Democratic governors, so they will keep us informed.
B Stieg
(2,410 posts)welcome to DU!
EarthFirst
(2,901 posts)...the next month is going to be a scene like nothing the majority of us have ever witnessed.
Evolve Dammit
(16,750 posts)LittleGirl
(8,287 posts)I think a month from now is going to be life changing.
Before the pandemic, and after the pandemic.
DanieRains
(4,619 posts)Perhaps?
JudyM
(29,251 posts)production, apparently ready to start shipping in 3 weeks. A number of companies are producing test kits so hopefully soon well have multiple sources even though its for the whole world. Beyond the pale that we in the US with a good lead time didnt jump all over this. Oh, thats right, its a Dem hoax. And because itll be over in a April when the weather warms up.
Igel
(35,332 posts)If the grownups are in charge, it won't be bad. It'll be like a bad flu season with more than the usual number of hospitalizations.
Note that every large-scale testing run of people that *might* have contracted the disease shows a large number of people with COVID-19 but without symptoms--but that's a larger sample that's still not random. So a S. Korean sample was heavily weighted for adults, while we know kids tend to have a much greater chance of being asymptomatic. This pulls the hospitalization rate way down for most groups, but it's the kind of number that professionals have trouble with because it's a guess. And we can't stand uncertainty.
80% report relatively mild symptoms. But that's only 80% of the people reporting *any* symptoms. Most assume that that's 80% of the people with the virus, a much smaller cohort. The fact that it's been spreading for weeks unnoticed is actually a good sign for the severity of the illness, however much it may lead to panic by underinformed people who need to be confident they're smarter than the average bear. The subcohorts showing severe symptoms fall into specific categories--think "intersectionality" when it comes to risk. But the media reports gloss right over that, because it produces more viewership and more panic.
I suspect that when the dust settles and the floors are mopped the response from competent health authorities will be that China took all the proper steps for a disease that was truly, truly dangerous, albeit a bit late. But that this will turn out to be one that didn't merit all the panic building and panic oppression. Some of it was sincerely "we must address the health crisis" and part of it was eye candy for those who doubted Xi & company, "we must be seen to address the health crisis" and show that they were all studly "take charge" sorts of folk after looking like wusses with both thumbs up their collective butts.
If the idjits are in charge, it'll be a CF. People will panic, buy stuff they don't need, creating shortages. They might make caregivers' work harder, and even turn on those they suspect of carrying the "plague," because, after all, each individual is more important than the collective.
Right now smart money's on the idjits.
McKim
(2,412 posts)Here in Oregon I have to isolate. Sadly I was sick with one virus October to December then another one January to last week. This has meant a lot of time in bed and I missed a lot of social events.
These viruses made my asthma worse and I have to use a twice a day inhaler. So at 74 I decided to self isolate until this is over. I had to cancel a trip to Spain, my Spanish class at the university, singing lessons and parties and its back to being along a lot.
So now I will clean out the basement, paint some interior rooms and woodwork. Not fun but it will cheer me up. Time to lay in some good books and stay active on the stationary bike and weights. I advise others to think about isolating if they are elderly.
LittleGirl
(8,287 posts)Painting the hallway and getting the garden ready for the early spring were going to have.
Take care.
appalachiablue
(41,161 posts)demigoddess
(6,642 posts)cannabis_flower
(3,764 posts)If they tested cases of people who were hospitalized with "the flu" previous to the China outbreak and they were found to be Coronavirus. I picked up a guy at Memorial Hermann at the Medical Center in Houston whose 29 year old son had contracted flu and had gotten pneumonia and sepsis and had been in the hospital 10 weeks. They should be testing these people if they hadn't already.
itsrobert
(14,157 posts)to stop immigrants coming thru the Mexico/US Border. That should stop any further spreading in the US.
Dopers_Greed
(2,640 posts)And Trump is on the record saying "don't worry" and "it's a hoax".
He now owns this.
MineralMan
(146,322 posts)pretty much everywhere. The lack of testing has limited the number of cases being reported. Now that the testing protocol is expanding, we'll learn of more cases.
Bottom line on this is that you cannot identify the disease with any level of sureness without testing, because its symptoms are similar to other diseases.
As more and more cases are discovered, including subclinical infections, I believe the mortality rate for the disease will drop.