General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsAnticancer activity of cannabinoids Journal of the National Cancer Institute, Vol. 55, No. 3,
from 1975.
"Summary --- Lewis lung adenocarcinoma growth was retarded by the oral administration of delta-9-tetrahydrocannabinol, delta-8-tetrahydrocannabinol, and cannabinol (CBN), but not cannabidiol (CBD). Animals treated for 10 consecutive days with delta-9-THC, beginning the day after tumor implantation, demonstrated a dose-dependent action of retarded tumor growth. Mice treated for 20 consecutive days with delta-8-THC and CBN had reduced primary tumor size. CBD showed no inhibitory effect on tumor growth at 14, 21, or 28 days. Delta-9-THC, delta-8-THC, and CBN increased the mean survival time (36% at 100 mg/kg, 25% at 200 mg/kg, and 27% at 50 mg/kg;, respectively), whereas CBD did not. Delta-9-THC administered orally daily until death in doses of 50, 100, or 200 mg/kg did not increase the life-spans of (C57BL/6 X DBA/2) F (BDF) mice hosting the L1210 murine leukemia. However, delta-9-THC administered daily for 10 days significantly inhibited Friend leukemia virus-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for actinomycin D. Experiments with bone marrow and isolated Lewis lung cells incubated in vitro with delta-8-THC and delta-9-THC showed a dose-dependent (10 -4 10 -7) inhibition (80-20%, respectively) of tritiated thymidine and 14C -uridine uptake into these cells. CBD was active only in high concentrations (10 -4). ----J Natl Cancer Inst 55: 597-602, 1975. "
http://www.drugpolicycentral.com/bot/pg/cancer/THC_cancer_sep_1975.htm
tridim
(45,358 posts)wildbilln864
(13,382 posts)maybe someone else will?
lunasun
(21,646 posts)Now this reads THC .
I don't have cancer or tumor but thanks very interesting that this was under prohibition and turns out to be a natural medicine .
Guess I was confused I always see these talks about CBD oil. But maybe that is what they are referring to as CBD in high concentrations
wildbilln864
(13,382 posts)effective for epilepsy and seizures. Look up Charlottes Web.
lunasun
(21,646 posts)Posted
Not only university research dollar but fed gov too
2014
Research funded by the NIH is actively investigating the possible therapeutic uses of THC, CBD, and other cannabinoids to treat autoimmune diseases, cancer, inflammation, pain, seizures, substance use disorders, and other psychiatric disorders.
wildbilln864
(13,382 posts)nationalize the fed
(2,169 posts)Cancer.gov:
Have any preclinical (laboratory or animal) studies been conducted using Cannabis or cannabinoids?
Preclinical studies of cannabinoids have investigated the following activities:
Antitumor activity
Studies in mice and rats have shown that cannabinoids may inhibit tumor growth by causing cell death, blocking cell growth, and blocking the development of blood vessels needed by tumors to grow. Laboratory and animal studies have shown that cannabinoids may be able to kill cancer cells while protecting normal cells.
A study in mice showed that cannabinoids may protect against inflammation of the colon and may have potential in reducing the risk of colon cancer, and possibly in its treatment.
A laboratory study of delta-9-THC in hepatocellular carcinoma (liver cancer) cells showed that it damaged or killed the cancer cells. The same study of delta-9-THC in mouse models of liver cancer showed that it had antitumor effects. Delta-9-THC has been shown to cause these effects by acting on molecules that may also be found in non-small cell lung cancer cells and breast cancer cells.
A laboratory study of cannabidiol (CBD) in estrogen receptor positive and estrogen receptor negative breast cancer cells showed that it caused cancer cell death while having little effect on normal breast cells. Studies in mouse models of metastatic breast cancer showed that cannabinoids may lessen the growth, number, and spread of tumors.
A laboratory study of cannabidiol (CBD) in human glioma cells showed that when given along with chemotherapy, CBD may make chemotherapy more effective and increase cancer cell death without harming normal cells. Studies in mouse models of cancer showed that CBD together with delta-9-THC may make chemotherapy such as temozolomide more effective...
http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page2
Did you know that the US Gov holds a patent on the use of Cannabinoids?
#6630507 LINK to US PATENT AT USPTO.GOV
Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases..
Awarded in 2003 and assigned to the US DHHS
A company called Kannalife (http://kannalife.com) has been awarded part of this patent
uppityperson
(115,679 posts)wildbilln864
(13,382 posts)snooper2
(30,151 posts)But I think that is reserved for just one poster LOL
http://www.democraticunderground.com/?com=forum&id=1164
uppityperson
(115,679 posts)group with little use. 2 different things.
Here's another low volume one.http://www.democraticunderground.com/?com=forum&id=1070
wildbilln864
(13,382 posts)the cash keeps coming in, but if you're cured it stops! And if you could grow your own cure in your own back yard....well...They'd lose billions. And many industries have much to lose if cannabis become legal nation wide.
lunasun
(21,646 posts)wildbilln864
(13,382 posts)At least I hope so.
lunasun
(21,646 posts)Truth will win out somewhere else and when synthesized and sold by Bayer or J & J maybe you can post without lock
truedelphi
(32,324 posts)To give us our own forum, the way some here have a religion forum.
I thought "Alternative health" would be a great thing. (This was before several others here have given up in total and carry their ideas about health to Facebook and other forums rather than here.) I thought it would be good if people I knew on DU that had the same views I did could express them without the trolls showing up and locking and jeering and being derisive.
The Admins response was that any of us who had alternative ideas about health could go to the Astrology and spirituality forum.
Which is why ninety percent of my blogging is now over at FBook.
Rex
(65,616 posts)You could post a reply from Dr. phd and it wouldn't make any difference...GD has gatekeepers that will not tolerate anything out of what they want to see here. Their behavior is why we don't have a meta forum anymore, so now all they can do is sulk and pounce in GD and sadly they picked you.
wildbilln864
(13,382 posts)Rex
(65,616 posts)that died from stage 4 pancreatic cancer. A few months before she passed away, she told me that MJ was the ONLY thing that made the 'tightness' as she called it inside her loosen up and relax and take some of the pain away. NOT morphine or any other drug.
She never smoked or did any kind of illegal drug up until that point, yet she was a lifetime smoker of cigarettes...which are of course totally legal.
the two most deadly drugs in the world(alcohol & nicotine) are legal yet cannabis which you cannot even OD on and has never been proven to harm anyone is illegal. Strange that.
Rex
(65,616 posts)when it comes to just talking about the possible positive health effects from THC. Something one would expect from Big Pharma bootlickers.
wildbilln864
(13,382 posts)DisgustipatedinCA
(12,530 posts)I'd really like to know who has decided that cannabis isn't an effective medicine, because the research that keeps coming out says otherwise. Is someone trying to turn this into "woo"? If so, they may need a patented Skittles ass-kicking.
Rex
(65,616 posts)so they went to a higher power and demanded the thread be locked. Just my guess. Seems to be the pattern over the years. Don't like something in GD? Label it as 'woo' and start a campaign to get it locked.
wildbilln864
(13,382 posts)truedelphi
(32,324 posts)wildbilln864
(13,382 posts)wildbilln864
(13,382 posts)NuclearDem
(16,184 posts)There is a strong and persistent presence on the internet arguing that cannabis can cure cancer. For example, there are numerous videos and unverified anecdotes claiming that people have been completely cured of cancer with cannabis, hemp/cannabis oil or other cannabis derivatives.
Despite what the supporters of these sources may claim, videos and stories are not scientific evidence for the effectiveness of any cancer treatment. Extraordinary claims require extraordinary evidence YouTube videos are emphatically not scientific evidence, and we are not convinced by them.
Based on the arguments presented on these kinds of websites, its impossible to tell whether these patients have been cured by cannabis or not. We know nothing about their medical diagnosis, stage of disease or outlook. We dont know what other cancer treatments they had. We dont know about the chemical composition of the treatment they got. And we only hear about the success stories what about the people who have tried cannabis and not been cured? People who make these bold claims for cannabis only pick their best cases, without presenting the full picture.
This highlights the importance of publishing data from scientifically rigorous lab research and clinical trials. Firstly because conducting proper clinical studies enables researchers to prove that a prospective cancer treatment is safe and effective. And secondly because publishing this data allows doctors around the world to judge for themselves and use it for the benefit of their patients.
This is the standard to which all cancer treatments are held, and its one that cannabinoids should be held to too. Internet anecdotes and videos prove nothing and benefit no-one we need reliable, scientific research, which (as discussed above) is exactly what is going on.
Its all a big conspiracy you dont want people to be cured!
As weve previously said, accusations that we are somehow part of a global conspiracy to suppress cancer cures are as absurd as they are offensive. Not only to the thousands of our scientists, doctors and nurses who are working as hard as they can to find more effective treatments for the complex set of challenging diseases we call cancer, but also the hundreds of thousands of people in the UK and beyond who support this life-saving work through generous donations of money, energy and time.
Our aim is to beat cancer through research
Our aim is to beat cancer, and we believe that the best way to do this through rigorous scientific research aimed at understanding cancer on a biological level and working out how to prevent, detect and treat it more effectively. This approach has helped to change the face of cancer prevention, diagnosis, treatment, leading to a doubling in survival rates over the past 40 years.
As a research-based organisation, we want to see reliable scientific evidence to support claims made about any cancer treatment, be it conventional or alternative. The claims made for many alternative cancer therapies still require solid evidence to support them, and it often turns out that these miracle cures simply dont work when theyre put to the test.
This doesnt mean theres a conspiracy to suppress the True Cure for Cancer it means that doctors and researchers want to see solid evidence that the claims made by people peddling these treatments are true.
This is vital because lives are at stake. Some people may think that a cancer patient has nothing to lose by trying an alternative treatment, but there are big risks.
Whats the harm? Theres nothing to lose.
If someone chooses to reject conventional cancer treatment in favour of unproven alternatives, including cannabis, they may miss out on treatment that could save or significantly lengthen their life. They may also miss out on effective symptom relief to control their pain and suffering, or the chance to spend precious time with their loved ones.
Furthermore, many of these unproven therapies come at a high price, and are not covered by the NHS or medical insurance. And, in the worst cases, an alternative therapy may even hasten death. Cannabis is also an illegal (class B) drug in the UK.
Although centuries of human experimentation tells us that naturally-occurring cannabinoids are broadly safe, they are not without risks. They can increase the heart rate, which may cause problems for patients with pre-existing or undiagnosed heart conditions. They can also interact with other drugs in the body, including antidepressants and antihistamines. And they may also affect how the body processes certain chemotherapy drugs, which could cause serious side effects.
There is also a reported case where a Dutch lung cancer patient took cannabis extract that had been bought from a street source. Within a matter of hours she was in hospital in a coma. This highlights the risks of taking street cannabis extracts of unknown concentration and quality in an uncontrolled way, and accentuates the need for careful research into how best to use cannabinoids for treating patients.
Furthermore, there are other risks associated with using black market or home-made preparations of cannabis, particularly cannabis oil. For example, there may be toxic chemicals left from the solvents used in the preparation process. There is also a risk that pesticides found in cannabis crops may be concentrated in these preparations recent research from California suggests high rates of such contaminants in samples from a range of different sources.
Finally, we are also aware of internet scams by people offering to sell cannabis preparations. As well as the risk of getting something with completely unknown chemical or medicinal properties and unknown effectiveness, there is a strong chance of receiving nothing at all.
It is a sad fact that although huge progress has been made over recent years, many thousands of people in the UK lose their lives to cancer every year a situation that we urgently want to change through research. But when conventional treatment fails, there is little chance that turning to an unproven alternative touted on the internet will provide a cure.
People who prey on cancer patients, whether they work for pharmaceutical companies or push bullshit cannabis "cures" on the internet are the lowest forms of scum on this earth.
wildbilln864
(13,382 posts)deal! If you don't like it don't read it.
NuclearDem
(16,184 posts)You're pushing bullshit and giving false hope to people suffering with cancer and their families. That is utterly fucking despicable and you need to be called out on it.
Every dollar someone spends on one of these crank cannabis "cures" is a dollar they can't spend on a legitimate treatment. People who push this bullshit are going to get people killed, if they haven't already.
You should be utterly ashamed of yourself, but I doubt that's possible.
wildbilln864
(13,382 posts)you offer only your opinion!
NuclearDem
(16,184 posts)That's the opinion of thousands of researchers who are actively working on finding a cure for cancer and who are sick to death of people pushing this bullshit.
This "cannabis cures cancer" nonsense is just a sick tactic of a very awful fringe of the legalization movement to paint cannabis as a cure for just about fucking everything. There's no broad scientific evidence that shows cannabis cures cancer.
Fuck, this is utterly disgusting.
Jesus Malverde
(10,274 posts)Some people are like a broken record, all pops and crackle, no music at all.
Keep playing my brother!
truedelphi
(32,324 posts)Cannabis has the ability to help a mammalian body release enzymes that attack cancer cells. It is that easy.
Go Vols
(5,902 posts)NuclearDem
(16,184 posts)Those videos are not scientific evidence.
wildbilln864
(13,382 posts)wildbilln864
(13,382 posts)> > http://www.fuoriluogo.it/medicalcannabis/documenti/cancertherapy.pdf
> >
> > http://files.iowamedicalmarijuana.org/science/cancer/Massi%202004.pdf
> >
> > http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.334.2420&rep=rep1&type=pdf
> >
> > http://www.atsjournals.org/doi/abs/10.1164/ajrccm.156.5.9704146#.VMl_Tizp0SU
> >
> > http://www.fasebj.org/content/15/14/2745.short
> >
Go Vols
(5,902 posts)but it hurts no one to try it unlike other drugs.
The more that say it works makes me think they may be on to something.
It is definitely a mood altering substance per my experience,as I am pretty happy right now.
wildbilln864
(13,382 posts)me too bro, lol...
NuclearDem
(16,184 posts)does fucking hurt people, because it means they're not spending money on effective treatments.
wildbilln864
(13,382 posts)are you saying the Journal of the American Cancer Institute isn't scientific? Really!?
Go Vols
(5,902 posts)that all the late night commercials promote to get better health.
I can grow MJ and the cost is minimal.
Bandit
(21,475 posts)other EXTREMELY expensive drugs. Pot is not only fairly cheap, comparatively, but it also helps restore appetite, and attitude.. Your drugs not so much..
NuclearDem
(16,184 posts)is obviously evidence of being a Big Pharma shill.
You got me, champ.
wildbilln864
(13,382 posts)deny all you want. It's been around for at least 8000 years and hasn't harmed anyone yet. And the science finds it may be very beneficial in a great many ways.
NuclearDem
(16,184 posts)Because you need a hell of a lot more evidence, not to mention more clinical trials, to even begin to try to back up claims that marijuana cures cancer.
It's a huge damn leap from "hasn't hurt anyone yet" (vague enough statement that it can't really be challenged, by the way, nice work) to "cures cancer."
wildbilln864
(13,382 posts)so let's legalize cannabis and test the claims.
NuclearDem
(16,184 posts)And if it turns out cannibinoids can "cure cancer", then I will spin on a dime and accept that. But right now, you have absolutely zero basis to be pushing those claims.
Response to NuclearDem (Reply #73)
wildbilln864 This message was self-deleted by its author.
NuclearDem
(16,184 posts)You've got to be fucking kidding me.
wildbilln864
(13,382 posts)wildbilln864
(13,382 posts)NuclearDem
(16,184 posts)This is like talking to a brick wall.
wildbilln864
(13,382 posts)have a great night!
Politicalboi
(15,189 posts)Just because MJ isn't taken seriously in the medical profession doesn't mean it doesn't work. Studies done in 1974 have proven MJ shrinks cancerous tumors, but I guess those snake oil studies were bullshit too. Our government has lied to us about MJ for decades, gate way drug, loss of brain cells bullshit. They're the snake oil people. If I had cancer I would see a real MJ doctor and use MJ for treatment. If I needed other treatment I would do that too if it helped. Your post here would deter someone who might even think of using MJ. Full of What if's bullshit. If you have cancer, don't go looking on the street or internet for treatment. Go to Ca, Co, or any other state where medical MJ is accepted and works.
NuclearDem
(16,184 posts)Well, color me convinced! Here I was thinking such an extraordinary claim required a hell of a lot more evidence than one study, but lookie here, I've got so much egg on my face you can slap me with a frying pan and call me an omelet!
wildbilln864
(13,382 posts)and FYI there's been more than just one. But you knew that right? You didn't?
NuclearDem
(16,184 posts)God have mercy on your soul.
wildbilln864
(13,382 posts)Now there's some woo! IMHOOC.
Go Vols
(5,902 posts)SammyWinstonJack
(44,130 posts)truedelphi
(32,324 posts)Last edited Wed Jan 28, 2015, 03:16 AM - Edit history (1)
"proven" that autism is not caused by vaccines. Never mind that the parameters of the two studies make them rather worthless as real science.
But "two studies" makes anyone who is part of Big Pharma Rah rah rah camp very pleased. That is all that is needed to prove the safety of something that Big Pharma needs for its profit margins -two studies.
As far as cannabis studies, the fact that marijuana has been a schedule one drug means that it has been very difficult to have anyone get the funding that is needed and also the ability to legally obtain the cannabis in order to do the study.
wildbilln864
(13,382 posts)truedelphi
(32,324 posts)Go Vols
(5,902 posts)sorta turns me off on what big pharma says about most drugs they push.
Response to truedelphi (Reply #45)
Go Vols This message was self-deleted by its author.
NuclearDem
(16,184 posts)So full of fail I don't even know where to begin.
Go Vols
(5,902 posts)put to task the number of studies on drugs,not another agenda.
longship
(40,416 posts)Last edited Wed Jan 28, 2015, 06:00 AM - Edit history (2)
Only two studies, eh?
Click through here: Vaccines and Autism. It's not nice to try to fool science. One ends up being the fool. Make sure you scroll down to the sample of the multitude of peer reviewed research that show no connection between vaccines and negative outcomes, including autism.
And by the way, one might want to peruse Brian Deer's expose of the anti-vaxxer's god, Andrew Wakefield. Exposed: Andrew Wakefield and the MMR-Autism fraud. He lost his license to practice medicine in the UK because of this. Now he is practicing his utter quackery here in quack friendly USA.
There is no alternative medicine. There is just medicine, based on science.
Jesus Malverde
(10,274 posts)NuclearDem
(16,184 posts)I trust some random asshole on YouTube a lot more!
Jesus Malverde
(10,274 posts)Not much.
Let me know when it gets rescheduled.
NuclearDem
(16,184 posts)But that still doesn't make any sense, considering the Feds themselves commissioned medical marijuana studies back in the 90s.
longship
(40,416 posts)There is no alternative medicine. There is only medicine, based on science.
And one study does not make an hypothesis science. One must look at the scientific literature as a whole to determine what holds up. That's the big problem with AltMed. Their proponents do not understand this simple fact.
Plus, there is the problem that there will never, ever be a single cure for cancer because cancer is not one thing. But people generally do not understand that, so cancer quacks can get their claws into those whom need help the most.
This is disgusting and does not belong here on this forum.
wildbilln864
(13,382 posts)you don't get to decide that! you can whine some more about it however.
longship
(40,416 posts)You can make shit up, but the universe is what the universe is. And there are no universal cancer cures, no matter what quacks say.
wildbilln864
(13,382 posts)does not mean it doesn't exist. Even though egos may convince you otherwise. I am not making anything up. You are. I merely pointed out research that seems to be very promising. An avenue that needs exploring. But people need to be made aware of the potential benefits in order to support legalization which will lead to more research.
Dreamer Tatum
(10,926 posts)you'd give significantly fewer fucks about cannabinoids.
If you want to smoke pot, smoke pot. Christ.