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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsArtificial Spleen Removes Ebola, HIV Viruses and Toxins From Blood Using Magnets
http://www.ibtimes.co.uk/artificial-spleen-removes-ebola-hiv-viruses-toxins-blood-using-magnets-1465585Harvard scientists have invented a new artificial spleen that is able to clear toxins, fungi and deadly pathogens such as Ebola from human blood, which could potentially save millions of lives.
To overcome this, researchers have invented a "biospleen", a device similar to a dialysis machine that makes use of magnetic nanobeads measuring 128 nanometres in diameter (one-five hundredths the width of a single human hair) coated with mannose-binding lectin (MBL), a type of genetically engineered human blood protein.
The researchers also tested the bio-spleen on rats that had been infected by toxins and viruses such as E. coli and S. aureus. After just five hours of filtering, 90% of the toxins and pathogens had been removed from the rats' bloodstreams and 90% of the treated rats survived.
newfie11
(8,159 posts)And good timing
LiberalEsto
(22,845 posts)and I hope we can manufacture enough of them in time to save people in Africa.
AngryAmish
(25,704 posts)Dr Hobbitstein
(6,568 posts)MattBaggins
(7,904 posts)WestCoastLib
(442 posts)tclambert
(11,087 posts)Or maybe you wondered how they function in this particular application. The tiny nano-beads coated with something that binds to the pathogens are themselves magnetic or made of something that will stick to magnets. Then you can use magnets to collect the contaminated nano-beads. Pathogen sticks to antigen which sticks to nano-bead which sticks to magnet.
Like I said, witchcraft.
NuclearDem
(16,184 posts)Initech
(100,079 posts)Duer 157099
(17,742 posts)the magnetic particles are coated with stuff that binds to the bad stuff and then can be pulled away using other magnets.
magnet + antibody (for example)
antibody binds to antigen (virus, bacteria, whatever)
use magnet to separate antigen+antibody+magnet from the other material (blood, whatever)
magical thyme
(14,881 posts)Progressive dog
(6,904 posts)Last edited Tue Sep 16, 2014, 11:08 AM - Edit history (1)
Ebola is a virus and the abstract (linked from ibtimes) does not mention viruses of any kind. (true but ebola is mentioned in Nature article)
Mother Jones investigated IBTimes, the article is in May-June issue. Personally, I avoid media outlets with close links to religious cults.
( I still don't like IBTimes)
stevenleser
(32,886 posts)freshwest
(53,661 posts)Progressive dog
(6,904 posts)in Nature that the IBTimes linked to, and jumped to a wrong conclusion. Nature did mention Ebola in an article.
muriel_volestrangler
(101,320 posts)('over 90 pathogens - different types of bacteria, fungi, viruses, parasites and toxins'). But I think they have to engineer the molecule for each new target.
The press release - more reliable: http://wyss.harvard.edu/viewpressrelease/166
And Nature does quote the team leader in an article:
http://www.nature.com/news/artificial-spleen-cleans-up-blood-1.15917
alcibiades_mystery
(36,437 posts)stevenleser
(32,886 posts)Included this in my FB post of this article!
Iliyah
(25,111 posts)Nice to get some good news every once in a while.
valerief
(53,235 posts)too expensive.