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sinkingfeeling

(51,457 posts)
Tue Sep 16, 2014, 09:48 AM Sep 2014

Artificial Spleen Removes Ebola, HIV Viruses and Toxins From Blood Using Magnets

http://www.ibtimes.co.uk/artificial-spleen-removes-ebola-hiv-viruses-toxins-blood-using-magnets-1465585

Harvard scientists have invented a new artificial spleen that is able to clear toxins, fungi and deadly pathogens such as Ebola from human blood, which could potentially save millions of lives.

To overcome this, researchers have invented a "biospleen", a device similar to a dialysis machine that makes use of magnetic nanobeads measuring 128 nanometres in diameter (one-five hundredths the width of a single human hair) coated with mannose-binding lectin (MBL), a type of genetically engineered human blood protein.

The researchers also tested the bio-spleen on rats that had been infected by toxins and viruses such as E. coli and S. aureus. After just five hours of filtering, 90% of the toxins and pathogens had been removed from the rats' bloodstreams and 90% of the treated rats survived.
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Artificial Spleen Removes Ebola, HIV Viruses and Toxins From Blood Using Magnets (Original Post) sinkingfeeling Sep 2014 OP
That's fantastic newfie11 Sep 2014 #1
I hope this is the answer LiberalEsto Sep 2014 #2
How do magnets work? AngryAmish Sep 2014 #3
Ask ICP? Dr Hobbitstein Sep 2014 #4
Invisible hooks MattBaggins Sep 2014 #14
Magnetism WestCoastLib Sep 2014 #15
Witchcraft. tclambert Sep 2014 #17
Fucking magnets! NuclearDem Sep 2014 #18
Ask the juggalos, yo! Initech Sep 2014 #20
Assuming that is a serious question... Duer 157099 Sep 2014 #21
hope this works out. this could be the answer to antibiotic resistance. nt magical thyme Sep 2014 #5
It does not have anything to do with Ebola (yes it does-sorry) Progressive dog Sep 2014 #6
IBTimes report is about a peer reviewed article in a science magazine stevenleser Sep 2014 #7
Thank you! This will be a life saver for those who are given the chance to have it done. freshwest Sep 2014 #8
You are right, I read the abstract Progressive dog Sep 2014 #10
The Harvard video at the link does mention 'viruses' in the list of possible targets muriel_volestrangler Sep 2014 #12
How has nobody posted this yet???? alcibiades_mystery Sep 2014 #9
LMAO stevenleser Sep 2014 #11
K & R Iliyah Sep 2014 #13
Well, the wealthy will be taken care of. The rest of us? They'll say it's valerief Sep 2014 #16
This would be good for the Red Cross blood supply too. Spitfire of ATJ Sep 2014 #19
It sure would! CaliforniaPeggy Sep 2014 #22
 

LiberalEsto

(22,845 posts)
2. I hope this is the answer
Tue Sep 16, 2014, 09:51 AM
Sep 2014

and I hope we can manufacture enough of them in time to save people in Africa.

tclambert

(11,087 posts)
17. Witchcraft.
Tue Sep 16, 2014, 12:40 PM
Sep 2014

Or maybe you wondered how they function in this particular application. The tiny nano-beads coated with something that binds to the pathogens are themselves magnetic or made of something that will stick to magnets. Then you can use magnets to collect the contaminated nano-beads. Pathogen sticks to antigen which sticks to nano-bead which sticks to magnet.

Like I said, witchcraft.

Duer 157099

(17,742 posts)
21. Assuming that is a serious question...
Tue Sep 16, 2014, 03:24 PM
Sep 2014

the magnetic particles are coated with stuff that binds to the bad stuff and then can be pulled away using other magnets.

magnet + antibody (for example)

antibody binds to antigen (virus, bacteria, whatever)

use magnet to separate antigen+antibody+magnet from the other material (blood, whatever)

Progressive dog

(6,904 posts)
6. It does not have anything to do with Ebola (yes it does-sorry)
Tue Sep 16, 2014, 10:33 AM
Sep 2014

Last edited Tue Sep 16, 2014, 11:08 AM - Edit history (1)

Ebola is a virus and the abstract (linked from ibtimes) does not mention viruses of any kind. (true but ebola is mentioned in Nature article)
Mother Jones investigated IBTimes, the article is in May-June issue. Personally, I avoid media outlets with close links to religious cults.
( I still don't like IBTimes)

Progressive dog

(6,904 posts)
10. You are right, I read the abstract
Tue Sep 16, 2014, 11:03 AM
Sep 2014

in Nature that the IBTimes linked to, and jumped to a wrong conclusion. Nature did mention Ebola in an article.

muriel_volestrangler

(101,320 posts)
12. The Harvard video at the link does mention 'viruses' in the list of possible targets
Tue Sep 16, 2014, 11:13 AM
Sep 2014

('over 90 pathogens - different types of bacteria, fungi, viruses, parasites and toxins'). But I think they have to engineer the molecule for each new target.

The press release - more reliable: http://wyss.harvard.edu/viewpressrelease/166

And Nature does quote the team leader in an article:

Ingber says that the biospleen could also help to treat viral diseases such as HIV and Ebola, in which survival depends on lowering the amount of virus in the blood to a negligible level. His group is now testing the biospleen on pigs.

http://www.nature.com/news/artificial-spleen-cleans-up-blood-1.15917
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