Pssst...Wanna know who apparently is fine with their drug being used to kill people inexpertly...

[Snarkoleptic]

" (Akorn) Apparently is fine with their drug (Midazolam) being used to kill people inexpertly, in basically experimental measures all over the country now, at least 3 of which have been botched to the point of getting national headlines." - Rachel Maddow

Rachel clip here (the whole thing is worth watching, but skip to 2:51 if you're in a rush)
http://on.msnbc.com/1pfTd1w

They've heard from me and maybe they'll hear from you as well.
[e-mail]


Here's the page where Akorn proudly features this product.
http://www.akorn.com/prod_detail.php?ndc=17478-524-05

[Heidi]

1. Kick, kick, kick!!!

[oldandhappy]

2. Put AKORN into your search engine

and then click on contact. Otherwise you get a phishing warning. I did send a 'Shame' message. Thank you.

[snooper2]

3. not following this here, this drug is used to put people under

It's not the cocktail the asshole then receives that is supposed to put them to death----



CLINICAL PHARMACOLOGY
Midazolam is a short-acting benzodiazepine central nervous system
(CNS) depressant.
The effects of midazolam on the CNS are dependent on the dose
administered, the route of administration, and the presence or absence of
other medications. Onset time of sedative effects after IM administration
in adults is 15 minutes, with peak sedation occurring 30 to 60 minutes
following injection. In one adult study, when tested the following day, 73%
of the patients who received midazolam intramuscularly had no recall of
memory cards shown 30 minutes following drug administration; 40% had
no recall of the memory cards shown 60 minutes following drug
administration. Onset time of sedative effects in the pediatric population
begins within 5 minutes and peaks at 15 to 30 minutes depending upon
the dose administered. In pediatric patients, up to 85% had no recall of
pictures shown after receiving intramuscular midazolam compared with
5% of the placebo controls.
Sedation in adult and pediatric patients is achieved within 3 to 5 minutes
after intravenous (IV) injection; the time of onset is affected by total dose
administered and the concurrent administration of narcotic premedication.
Seventy-one percent of the adult patients in the endoscopy studies had
no recall of introduction of the endoscope; 82% of the patients had no
recall of withdrawal of the endoscope. In one study of pediatric patients
undergoing lumbar puncture or bone marrow aspiration, 88% of patients
had impaired recall vs 9% of the placebo controls. In another pediatric
oncology study, 91% of midazolam treated patients were amnestic
compared with 35% of patients who had received fentanyl alone.
When midazolam is given IV as an anesthetic induction agent, induction
of anesthesia occurs in approximately 1.5 minutes when narcotic
premedication has been administered and in 2 to 2.5 minutes without
narcotic premedication or other sedative premedication. Some
impairment in a test of memory was noted in 90% of the patients studied.
A dose response study of pediatric patients premedicated with 1.0 mg/kg
intramuscular (IM) meperidine found that only 4 out of 6 pediatric patients
who received 600 mcg/kg IV midazolam lost consciousness, with eye
closing at 108 ± 140 seconds. This group was compared with pediatric
patients who were given thiopental 5 mg/kg IV; 6 out of 6 closed their
eyes at 20 ± 3.2 seconds. Midazolam did not dependably induce
anesthesia at this dose despite concomitant opioid administration in
pediatric patients.

[Snarkoleptic]

6. It's been well documented that Midazolam was used (or misused) in this Arizona human experiment.

"...Arizona became the latest of four states to turn to another sedative, midazolam, first used for execution less than a year ago. Arizona used it in combination with a narcotic, hydromorphone. Midazolam, by itself or with hydromorphone, has led to flawed, drawn-out executions in three other states."

https://www.azcentral.com/story/news/local/arizona/2014/07/23/arizona-execution-botched/13070677/

[Avalux]

4. Versed. I've had it a few times for medical procedures.

Nothing wrong for using it for that purpose, it's actually a great drug. BUT....let's look at the approved FDA labeling:

Midazolam Injection USP is indicated:

intramuscularly or intravenously for preoperative sedation/anxiolysis/amnesia;
intravenously as an agent for sedation/anxiolysis/amnesia prior to or during diagnostic, therapeutic or endoscopic procedures, such as bronchoscopy, gastroscopy, cystoscopy, coronary angiography, cardiac catheterization, oncology procedures, radiologic procedures, suture of lacerations and other procedures either alone or in combination with other CNS depressants;
intravenously for induction of general anesthesia, before administration of other anesthetic agents. With the use of narcotic premedication, induction of anesthesia can be attained within a relatively narrow dose range and in a short period of time. Intravenous midazolam can also be used as a component of intravenous supplementation of nitrous oxide and oxygen (balanced anesthesia);
continuous intravenous infusion for sedation of intubated and mechanically ventilated patients as a component of anesthesia or during treatment in a critical care setting.
Midazolam is associated with a high incidence of partial or complete impairment of recall for the next several hours.

Nowhere does it say that midazolam is approved to kill people, so it's being used off label. The company has some control over that by being choosy about who purchases it, but that's difficult because it's a popular drug. The FDA needs to get involved.

[conservaphobe]

5. K&R for exposure. nt