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FarCenter

(19,429 posts)
Tue Oct 29, 2013, 07:45 AM Oct 2013

Fasting at Least Twice a Week Seen as Alzheimer’s Hedge

For the past year, Stuart Adams has been fasting twice a week. While he has lost 15 pounds, the real reason he’s depriving himself is to stave off brain disorders including schizophrenia and Alzheimer’s disease.

“There’s a virulent strain of madness running through my family, and I reckoned my chances of going down that route were pretty high,” said Adams, 43, a freelance translator and interpreter in London who learned of a possible link between Alzheimer’s and diet while watching a BBC documentary last year. “Anything that could help with that was of great interest.”

Fasting two or more days a week is catching on as people seek ways to avoid a range of ailments linked to obesity from dementia to cancer. Building on promising findings in studies of mice by the U.S. National Institute of Aging, researchers are planning the first studies in humans of fasting’s potential to stave off the onset of Alzheimer’s. That disease is just one of many in which scientists are making progress understanding how fasting may help prevent illness.

Because there is no cure for Alzheimer’s, which afflicts more than 35 million people, any possibility of prevention holds huge potential. Adams was inspired to try the diet last year after the BBC documentary called “Eat, Fast & Live Longer” cited a study in mice that suggested intermittent fasting could delay the onset of cognitive disorders.

The study was led by Mark Mattson, professor of neuroscience at Johns Hopkins University in Baltimore and senior investigator at the U.S. National Institute of Aging. Mattson is planning a new project to measure how fasting twice a week for two months affects human brain function and early signs of Alzheimer’s.


http://www.bloomberg.com/news/2013-10-29/fasting-at-least-twice-a-week-seen-as-alzheimer-s-hedge.html
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Fasting at Least Twice a Week Seen as Alzheimer’s Hedge (Original Post) FarCenter Oct 2013 OP
This seems rather ironic coming out so close to the food stamp cuts BuelahWitch Oct 2013 #1
Fasting is a how our body anticipates we will eat Shivering Jemmy Oct 2013 #2
But it is unlikely it would support the lifestyles of most people now BuelahWitch Oct 2013 #5
Exactly. ronnie624 Oct 2013 #12
There has been a lot of research on calorie restriction and longevity over the past decade FarCenter Oct 2013 #3
But this study is suggesting that people fast twice a week BuelahWitch Oct 2013 #4
People think many things. Bluenorthwest Oct 2013 #6
They shouldn't call it "fasting" if that's not what they really mean. Quantess Oct 2013 #8
In some versions, you eat a light dinner one day, skip breakfast and lunch, and then eat dinner FarCenter Oct 2013 #9
I used to have a "vegetables only" day (no potatoes, either) Quantess Oct 2013 #10
Various "de-tox" diets appear to work similarly FarCenter Oct 2013 #13
I didn't title the fucking article BuelahWitch Oct 2013 #15
I could possibly deal with fasting one day a week, if I really felt motivated. Quantess Oct 2013 #7
I was reading an article in a magazine about how Alzheimer's groups suggest liberal_at_heart Oct 2013 #11
A great many weight loss diets suggest not eating at night BuelahWitch Oct 2013 #16
no it's not really fasting but it still creates the same effect inducing neuronal autophagy. liberal_at_heart Oct 2013 #17
Not eating between dinner and break-fast is fasting. SalviaBlue Oct 2013 #22
If you did it every 4th day, you would probably be fine SoCalDem Oct 2013 #14
Fasting for at least one day is nothing. People HAVE had colonoscopies, right?! WinkyDink Oct 2013 #18
um.... NO. I haven't. Quantess Oct 2013 #21
Bah on typos! (Pssst...I hope you're younger than, say, 40!) WinkyDink Oct 2013 #23
Isn't resveratrol supposed to accomplish the same thing? Duer 157099 Oct 2013 #19
Similar in that they operate on the mTOR signaling complexes FarCenter Oct 2013 #20
intermittent fasting seems valid. Dr Mercola is ok with it too. upi402 Oct 2013 #24

Shivering Jemmy

(900 posts)
2. Fasting is a how our body anticipates we will eat
Tue Oct 29, 2013, 07:58 AM
Oct 2013

Early humans probably did not eat every day. And many animals operate such that they only eat when very hungry.

Fasting is probably one of a number of natural dietary modes.

BuelahWitch

(9,083 posts)
5. But it is unlikely it would support the lifestyles of most people now
Tue Oct 29, 2013, 08:12 AM
Oct 2013

When we go back to caveman ways I guess it will be ok. It is silly to suggest fasting two days a week would work for most people.

ronnie624

(5,764 posts)
12. Exactly.
Tue Oct 29, 2013, 11:48 AM
Oct 2013

I work sixty hours a week at a very active job, and I work out five times a week. Fasting is not an option.

 

FarCenter

(19,429 posts)
3. There has been a lot of research on calorie restriction and longevity over the past decade
Tue Oct 29, 2013, 08:02 AM
Oct 2013

Intermittent fasting has been studied for at least a few years, and various health benefits besides the one in the story have been attributed to it.

http://en.wikipedia.org/wiki/Intermittent_fasting

Fasting as a religious discipline has been done for millennia, and there is no indication that fasting for a day is harmful.

The science indicates that fasting up-regulates the process of autophagy by which the body disassembles the proteins in cellular organelles that have become damaged or dysfunctional. It does so to scavenge amino acids to use for growth and repair. Unlike sugars and fats, the body doesn't store very much excess protein for later use.

 

Bluenorthwest

(45,319 posts)
6. People think many things.
Tue Oct 29, 2013, 10:55 AM
Oct 2013

Did you read the article? The 'fast' most often suggested is actually not a full fast but a day of 500-1000 calories with limited fat intake. An actual fast is zero calories.

Quantess

(27,630 posts)
8. They shouldn't call it "fasting" if that's not what they really mean.
Tue Oct 29, 2013, 11:21 AM
Oct 2013

Restricted calorie diet on 2 days per week. Something like that sounds like a less confusing.

 

FarCenter

(19,429 posts)
9. In some versions, you eat a light dinner one day, skip breakfast and lunch, and then eat dinner
Tue Oct 29, 2013, 11:29 AM
Oct 2013

So you don't actually consume 0 calories on any given day, but you do go 24 hours without food.

You can also fast breakfast to breakfast or lunch to lunch depending on what suits you.

It is just that going 24 hours without food shifts your body into using stored resources, rather than what is entering your bloodstream and lymphatic system from your intestines.

Quantess

(27,630 posts)
10. I used to have a "vegetables only" day (no potatoes, either)
Tue Oct 29, 2013, 11:35 AM
Oct 2013

or an "apples only" day, while also drinking water and coffee. That works really well to keep your weight down, especially after a day of eating too much.

 

FarCenter

(19,429 posts)
13. Various "de-tox" diets appear to work similarly
Tue Oct 29, 2013, 11:49 AM
Oct 2013

In spite of the hype about cleansing your body of "chemicals", etc., the common factor may be that they don't include much protein.

As a result, your body depletes its circulating store of amino acids and switches to breaking down damaged cellular components in order to get more.

BuelahWitch

(9,083 posts)
15. I didn't title the fucking article
Tue Oct 29, 2013, 12:46 PM
Oct 2013

Nor did I post the OP. But I guess you got your jollies enough to attack me, didn't you? That's what matters.

Quantess

(27,630 posts)
7. I could possibly deal with fasting one day a week, if I really felt motivated.
Tue Oct 29, 2013, 11:18 AM
Oct 2013

2 days out of 7 seems like too much fasting, to me.

liberal_at_heart

(12,081 posts)
11. I was reading an article in a magazine about how Alzheimer's groups suggest
Tue Oct 29, 2013, 11:37 AM
Oct 2013

fasting for 12 hours like in between dinner and breakfast.

BuelahWitch

(9,083 posts)
16. A great many weight loss diets suggest not eating at night
Tue Oct 29, 2013, 12:50 PM
Oct 2013

Which does make sense, but it's not really "fasting."

SoCalDem

(103,856 posts)
14. If you did it every 4th day, you would probably be fine
Tue Oct 29, 2013, 11:53 AM
Oct 2013

Sometimes I fast accidentally.. When my husband is out of town, I often forget to eat..(appetite has slacked off a lot as I age)

 

WinkyDink

(51,311 posts)
18. Fasting for at least one day is nothing. People HAVE had colonoscopies, right?!
Tue Oct 29, 2013, 12:56 PM
Oct 2013

Last edited Thu Oct 31, 2013, 10:38 PM - Edit history (1)

Duer 157099

(17,742 posts)
19. Isn't resveratrol supposed to accomplish the same thing?
Tue Oct 29, 2013, 01:20 PM
Oct 2013

Resveratrol seems to induce the same biochemical events that occur with fasting.

 

FarCenter

(19,429 posts)
20. Similar in that they operate on the mTOR signaling complexes
Tue Oct 29, 2013, 02:09 PM
Oct 2013

But fasting may work directly via AMPK, and not via sirtuin.

upi402

(16,854 posts)
24. intermittent fasting seems valid. Dr Mercola is ok with it too.
Thu Oct 31, 2013, 10:42 PM
Oct 2013

youtube ' intermittent fasting '
or for a laugh ' fasting twins ' <- those guys are funny but not office friendly

Not catabolic if you eat in an 8 hour window daily. Hormonal response seems positive.

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