Per Wikipedia's entry on Jon Cryer:
Prior to the 2008 presidential election, Cryer attended a fundraiser hosted by the McCain campaign and, according to news reports, endorsed Senator John McCain. When Cryer did not make a public endorsement for the 2012 race, his spokeswoman said that the 2008 report aligning him with the Republican Party was a "mistake" and that Cryer is "not really political." He had attended events for both Republicans and Democrats "because he wanted to hear what both sides had to say."
With regards to presumptive 2016 GOP nominee Donald Trump, Cryer shared his feelings on the May 5, 2016, episode of the podcast Never Not Funny. Cryer stated, "I have been pointing out, and I have been screaming to the rooftops, that Donald Trump is the Charlie Sheen of politics. [...] I have to tell you, I love Charlie Sheen, I loved working with him when he was sober, but he was, he's full of shit. He has been full of shit, you know, he has serious addiction. You know, his addiction is obviously serious, drugs, and, but, Trump is just addicted to feeling important. You know, and I think if anybody is under the delusion that he cares about, uh, uh, anybody in America besides himself, they are, they are stoned and need to rethink their priorities, 'cause he's, you know, 'cause it's just ridiculous that's he's gotten as far as he has."
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