an international group of scientists in the field of Vitamin D research from top North American universities have banded together to alert the public about widespread Vitamin D deficiency and the importance Vitamin plays in health. They are deeply concerned that doctors have dropped the ball and have not kept abreast of the research.
The organization is called GrassRoots Health
http://www.grassrootshealth.net/# With regard specifically to Vitamin D and the flu:
A number of studies have addressed Vitamin D as an anti-infective agent:
"It is now known that vitamin D stimulates the secretion of natural antibiotics known as ‘anti-microbial peptides’. This gives vitamin D the potential to combat a range of infections.
Recently, the role of vitamin D as an anti-infective agent was assessed in the form of a review <2>. 13 studies were reviewed, of which 9 were ‘double-blind and placebo-controlled’ – generally regarded as the best study design to discern whether a treatment has a real benefit or not. Some of these studies assessed the role of vitamin D in the treatment of tuberculosis.
Overall, the results showed that vitamin D therapy shows considerable potential in the treatment of tuberculosis. The results also showed vitamin D can be effective for the treatment of other infections, including flu and viral upper respiratory tract illnesses (e.g. cold). In addition, adverse events due to vitamin D supplementation were rare."
References
1. Martineau AR, et al. A Single Dose of Vitamin D Enhances Immunity to Mycobacteria American Journal of Respiratory and Critical Care Medicine. 2007;176:208-213
2. Yamshchikov AV, et al. Vitamin D for Treatment and Prevention of Infectious Diseases: A Systematic Review of Randomized Controlled Trials Endocr Pract. 2nd June 2009
Item
"Vitamin D is obviously immunoregulatory as manifested by its ability to reduce inflammation, (15) suppress and/or prevent certain autoimmune diseases, (16-18) reduce the risk for cancer, (12) and may even reduce the severity and frequency of infectious diseases, such as acute pneumonia in children.
Periodic assessment of serum 25-OH-vitamin D (25(OH)D) and serum calcium will help to ensure that vitamin D levels are safe and effective for health maintenance and disease prevention."
This quote is from
The clinical importance of vitamin D (cholecalciferol): a paradigm shift with implications for all healthcare providers
Publication: Original Internist 01-MAR-07
Several web sites that are very informative:
Vitamin D Council
http://www.vitamindcouncil.org/The doctor who created Vitamin D Council is a psychiatrist at a Californian prison for the criminally insane. Prisoners in his ward have for years been getting 2000 IUs Vit D daily because of their very limited time outside. Back in the 90s he noticed prisoners in his ward didn't get a flu that was infecting others across the state so he contacted Canada's leading Vitamin D researcher at U of T Reinhold Vieth and they published a paper. Both he and Vieth as well as many other D researchers have since become crusaders about Vitamin D.
According to Dr Cannell at Vit D Council: Take enough Vitamin D3 to get your 25(OH)D level above substrate starvation levels which is 50 ng/mL US (125 nmol/L Canada).
Another informative site is FLuTracker
http://www.flutrackers.com/forum/index.php Call to Action Re GrassrootsHealth
The following are the researchers from top North American universities who are invloved with grassrootshealth mentioned earlier, below the list is their call to action:
University of California Scientists Panel
University of California Davis
Bruce D. Hammock, Ph.D.
Hari A. Reddy, Ph.D.
Ray Rodriguez, Ph.D.
University of California
Los Angeles
John Adams, M.D.
Milan Fiala, M.D.
Martin Hewison, Ph.D.
H. Phillip Koeffler, M.D.
Keith C. Norris, M.D.
University of California Riverside
Mathew Mizwicki, Ph.D.
Anthony W. Norman, Ph.D.
Laura P. Zanello, Ph.D.
University of California
San Diego
Richard L. Gallo, M.D., Ph.D.
Cedric F. Garland, Dr. P.H.
Frank C. Garland, Ph.D.
Edward D. Gorham, Ph.D.
Tissa Hata, M.D.
University of California
San Francisco
David Gardner, M.S., M.D.
Bernard P. Halloran, Ph.D.
National Scientists Panel
Atascadero State Hospital
John J. Cannell, M.D.
Boston University
School of Medicine
Michael F. Holick, Ph.D., M.D
Creighton University
Robert P. Heaney, M.D.
Joan M. Lappe, Ph.D., R.N.
Harvard School
of Public Health
Edward Giovannucci, M.D., ScD.
Walter C. Willett, Dr. P.H., M.D.
McGill University
John H. White, Ph.D.
Medical University
of South Carolina
Bruce W. Hollis, Ph.D.
Roswell Park
Cancer Institute
Candace Johnson, Ph.D.
Donald L. Trump, M.D.
Society for Medical Information and Prevention
Joerg Spitz, M.D.
Sunlight, Nutrition and Health Research Center
William B. Grant, Ph.D.
University of Alberta
Gerry Schwalfenberg, M.D., CCFP
University of Saskatchewan
Susan J Whiting, Ph.D.
University of Toronto,
Mt Sinai Hospital
Reinhold Veith, Ph.D.
The Call to Action:
"... We have concluded that the vitamin D status of most individuals in North America will need to be greatly improved for substantial reduction in incidence of cancer.
Epidemiological studies have shown that higher vitamin D levels are also associated with lower risk of Type I diabetes in children and of multiple sclerosis.
Several studies have found that markers of higher vitamin D levels are associated with lower incidence and severity of influenza and several other infectious diseases.
... New evidence indicates that the intake should be 2000 IU per day. Intake of 2000 IU/day is the current upper limit of the National Academy of Sciences, Institute of Medicine, Food and Nutrition Board.
New evidence also indicates that the upper limit should be raised substantially. The levels that are needed to prevent a substantial proportion of cancer would also be effective in substantially reducing risk of fractures, Type I childhood diabetes and multiple sclerosis. Greater oral intakes of vitamin D3 may be needed in the aged and in individuals who spend little time outdoors, because of reduced cutaneous synthesis.
Choice of a larger dose may be based on the individual’s wintertime serum 25(OH)D level. For those choosing to have serum D tested, a target serum level should be chosen in consultation with a health care provider, based on the characteristics of the individual. An approximate guide-line for health care providers who choose to measure serum 25-hydroxyvitamin D in their patients would to aim for 40-60 ng/ml, unless there are specific contraindications. Contraindications are extremely rare, and are well known to physicians. No intervention is free of all risk, including this one. Patients should be advised of this, and advised in detail of risks that may be specific to the individual.
Any risks of vitamin D inadequacy considerably exceed any risks of taking 2000 IU/day of vitamin D3, which the NAS-IOM regards as having no adverse health effect."
http://www.grassrootshealth.net/documentation-scientistscall#