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berni_mccoy Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:34 PM
Original message
Stem cells successfully treated diabetes in mice
Edited on Wed Feb-20-08 04:36 PM by berni_mccoy
This is a fairly significant breakthrough. Still much work to be done, but it's one step closer to seeing a cure in our lifetime.

Stem cells successfully treated diabetes in mice

Human stem cells transformed into nearly normal insulin-producing cells when implanted into mice, possibly offering a way to treat diabetes long-term, researchers at a U.S. company reported on Wednesday.

http://www.msnbc.msn.com/id/23259462/from/ET/

For anyone who is interested in what living with Type 1 diabetes is like, please check out the video in my sig.
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BOSSHOG Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:36 PM
Response to Original message
1. But its immoral
Its just plain wrong. We don't need scientific advancements through research we only need Jesus.
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nels25 Donating Member (636 posts) Send PM | Profile | Ignore Wed Feb-20-08 04:42 PM
Response to Reply #1
2. Sigh
I no you are using sarcasm and I respect that but to all the others who actually believe what you wrote than I state SIGH!!

If it helps mankind methinks the good lord and his son might actually find it a positive but than that's just my 2 cents.
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BOSSHOG Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:46 PM
Response to Reply #2
4. I'm not concerned about your two cents
Its the zealots who thrive in a tax exempt status and urge and support my post. You know, the one's who will be first in line to get any medical advances we get from evil research.
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nels25 Donating Member (636 posts) Send PM | Profile | Ignore Wed Feb-20-08 05:05 PM
Response to Reply #4
8. Whoa calm down
I am not the enemy here.

I was not trying to be offensive.

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mac2 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 11:56 PM
Response to Reply #4
32. Evil research
so say your religion but not mine. Don't believe your clergy who thought the earth was flat at one point. They burned herbalists at the stake and lost the cures with them. They want control and the profits.
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berni_mccoy Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:43 PM
Response to Reply #1
3. I know you are being sarcastic, but I do know people who believe that.
I tell them to look at my two boys, both who have type 1, and tell them why they do not deserve to have this potential cure researched.
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BOSSHOG Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:48 PM
Response to Reply #3
5. Best wishes to your sons
and I continue to give my meager contributions to medical research. Anyone who opposes stem cell research should be locked in the Alzheimers Ward of a Nursing Home for six months and then tell us all about the value of life.
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samplegirl Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:50 PM
Response to Reply #3
6. I agree
what if it were Bush's daughters??? I've watched my brother suffer with this most of his life and I believe anyone who has it deserves anything that give them a chance to find a cure. It's a horrible disease.
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mac2 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 11:47 PM
Response to Reply #1
29. Not the Bible but your country maybe?
I don't pay taxes to have anyone's holy book protected or defended. Keep government and your god separate.
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BOSSHOG Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-21-08 07:31 AM
Response to Reply #29
34. I always
fail at sarcasm. I invite you to read my sig line.
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TheWatcher Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-21-08 07:53 AM
Response to Reply #34
35. Allow me, Good Sir.
:sarcasm:

:)

And I salute you for your sigline. :patriot:
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blondeatlast Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 04:59 PM
Response to Original message
7. The hope is closer than it ever has been. Too late for me, but not for your beautiful sons.
After a lifetime with Type 1 (diagnosed at 7; I spent most of my childhood testing my urine alone) I know that the childhood victims of insulin dependence will see the "cure."

It's what I live for. My regards to your sons and to you; that's quite a burden.

Science and hope will prevail at last. Count on it (and I pray a little, too!).
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kimmerspixelated Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 05:52 PM
Response to Reply #7
9. I've read many times that by purifying one's
diet and upping their exercise that diabetes is reversible. Also, something as simple as a teaspoon of a certain kind of cinnamon slashes your blood sugar by half. Just wondering if you have looked into other methods of treating yourself. Please don't flame. Trying to HELP!
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blondeatlast Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 05:54 PM
Response to Reply #9
10. Insulin has worked very well for me for 40 years. You aren't helping us find a cure.
Once in a while you post something worthwhile which is why I haven't ignored you.

Leave me alone about this crap. I'm alive and reasonably healthy--and you are apt to harm someone.

Please, just stop it, stop it, stop it.
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caligirl Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 09:44 PM
Response to Reply #10
24. Just offering you some moral support in this. Type 1 is autoimmune, killer cells go after
beta or the insulin producing cells.




TO THOSE WHO DO NOT GET IT LET ME BE CLEAR, NOTHING WE DID AS KIDS, NOTHING WE ATE, NOTHING WE FED OUR DIABETIC KIDS CAUSED TYPE1. IT IS NOT- IT IS NOT- CAUSED BY ANYTHING THEY DID OR DID NOT DO. IT IS AN IMMUNE SYSTEM DISEASE ONLY. IT IS COMPLETELY DIFFERENT FROM TYPE2 AND HAS ONLY THE BLOOD SUGAR CONTROL IN COMMON, NOT THE CAUSE, NOT THE TREATMENT UNLESS A TYPE 2 NEEDS INSULIN, IT CANNOT BE REVERSED. TYPE 1 IS PERMANENT NO MATTER THE EFFORT BY PARENTS THE Type 1 DIABETIC OR THE INSULIN.

As the numbers of type 2's increase, this can sometimes be reversed, the type 1 child faces increasing difficulty with the publics attitudes that somehow they deserve this. If type 2 diabetes is related to diet and excercise that surely the type 1 child often diagnosed at 12 or as young as infancy must be just as at fault. IGNORANCE. the type 1 is constantly faced with this and we are constantly trying to reeducate the public as they confuse a deadly disease with a disease of completely different etiology.

Its bad enough all we have to deal with as diabetic type 1's and parents of these kids.
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blondeatlast Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 11:51 PM
Response to Reply #24
31. Thank you. He 's done this before and he simply doesn't seem to get that my pancreas hasn't
made insulin for 41 years and I sincerely doubt it ever will again.

:hug:
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kimmerspixelated Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-21-08 05:21 PM
Response to Reply #10
36. I apologize profusely. I meant no harm at all!!!
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blondeatlast Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-21-08 05:27 PM
Response to Reply #36
37. Accepted--with a request, if I may. Please educate yourself that there are profound
differences between Type I (now known as Insulin Dependent) and Tyep 2 diabetes.

I hear the utrition thing from well meaning friends and acquaintances--and occasional quacks--over and over again. I know how much credence to give them if they don't know the differences between the two types of diabetes.

Synthesized insulin is virtually free of side effects and has saved millions for almost 100 years. It's literally a miracle drug.

A little sensitivity--and knowledge--will take you far. Thank you.
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demodonkey Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:13 PM
Response to Reply #9
12. Type 1 Diabetes is NOT reversible up to now. Your pancreas loses ability to produce insulin.
Edited on Wed Feb-20-08 06:15 PM by demodonkey

The islet cells that should be producing insulin fail, and they do not come back.

Maybe this stem cell work will make that come back possible.

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TreasonousBastard Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:26 PM
Response to Reply #9
15. Some type II's can be helped that way...
although the cinnamon thing is debatable. Type II is a catchall for a number of conditions, sometimes including the common gestational diabetes. Sometimes it goes away, sometimes it doesn't, but it is treatable to a great extent. And treated it must be or long-term effects can be blindness, kidney destruction, and gangrene. And death.

But, don't EVER suggest that a Type I diabetic can find an easy cure in the kitchen. Type I is a different disease entirely and is a nightmare that consumes one's life.

All of us, I's and II's, have been showered with magic cures for as long as any of us can remember (chromium picolate, Noni juice..) and all of them are scams brought to us by the occasionally well-wishing but hopelessly ignorant. If stem cell research does nothing more than find a good treatment for Type I, it will well be worth it.




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caligirl Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 10:06 PM
Response to Reply #15
27. Second your comments. My son Dx March 15, 2002. nt
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Avalon Sparks Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 08:19 PM
Response to Reply #9
22. That won't work for Type 1
Edited on Wed Feb-20-08 08:20 PM by Avalon Sparks
Type 1 diabetics generally cannot make insulin anymore. The beta cells in the pancreas are 'burned out' and can't make insulin. Diet and exercise and cinnamon isn't much help.

Eating low carb and exercise (especially weight lifting) can in most cases help those with type II diabetes. They are still making insulin (unless their beta cells burn out too). The bigger problem with most type II's is insulin resistance - meaning their bodies are resistant to the insulin they do make. Diabetes is progressive, but for Type II's the process may be slowed down a great deal with lifestyle changes. It's not really reversible because once your blood sugars get high enough to be in the abnormal range, there's already been years of damage to the overworked beta cells.
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mac2 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-21-08 01:30 AM
Response to Reply #9
33. Type II Diabetes can be cured or less by losing weight in some
people. When you are over weight some people's body struggles to burn the glucose efficiently. Your Pancreas can't keep up.

Type I Diabetes as far as I know has no cure but to take insulin.

I've heard about cinnamon but you have to have a good stomach for large amounts. It's worth a try. Thanks for the hint and caring.
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demodonkey Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:08 PM
Response to Original message
11. K&R for my beautiful, special, wonderful, Type 1 Diabetic brother Paul...
Edited on Wed Feb-20-08 06:10 PM by demodonkey


...who died from infection and a brain stem hemorrhage at age 49 on May 11, 2007. He was very special because in addition to having diabetes, Paul was high-functioning autistic. (And BTW he was a great Democrat, who loved to vote!)

Oh, DAMN I HOPE THEY CURE THIS DISEASE!

It will be too late for Paul, but maybe others will be saved in the future.



-------------------------

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blondeatlast Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:13 PM
Response to Reply #11
13. Your brother must have been amazing--was he able to handle the self-care?
I'm 47 and still going strong on insulin and it's too late for me as well, but the hope is there that no child born today need ever take another injection.

Very nice tribute to Paul. Thank you for sharing it.

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demodonkey Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:14 PM
Response to Reply #13
14. Yes- He could test his own blood sugar, and mix and inject his insulin.
Edited on Wed Feb-20-08 06:17 PM by demodonkey
Thank you -- he was amazing, and I miss him terribly.

:cry:

God bless you... keep safe and stay healthy.

:hug:

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PA Democrat Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:34 PM
Response to Reply #11
16. A kick in the memory of your brother and for all of those with diabetes
There is a boy with autism in my daughter's grade who also has diabetes. He's a great kid who plays drums in his brother's band and is a member of the chorus. I can't imagine the double worry of dealing with diabetes on top of autism.

It looks like your brother lived his too-short life to the fullest.
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mzmolly Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:50 PM
Response to Reply #11
19. Your brother was lovely.
I'm sorry about your loss demodonkey.
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Yellow Horse Donating Member (462 posts) Send PM | Profile | Ignore Wed Feb-20-08 06:46 PM
Response to Original message
17. Kick to fight Type 1 diabetes -- one of the worst killers we face.
Too many lives cut short.

Too much suffering.

Thank God for Banting & Best who discovered insulin, but if this cure comes to pass... well, just THANK GOD.
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mzmolly Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 06:48 PM
Response to Original message
18. Thanks Berni. My dh is type one. Has been since 13 years of age.
He's got a pump now and it works well for the most part. :hi:
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localroger Donating Member (663 posts) Send PM | Profile | Ignore Wed Feb-20-08 07:25 PM
Response to Original message
20. Your .sig brought tears to my eyes
Two years ago I discovered I have "syndrome X" which ironically despite being a much milder problem than Type I, isn't really treatable except by radical low-carbing and constant testing. My blood pressure dropped from 167/119 to 125/85 in a matter of weeks when I started eating to correct it. Lovely thing to learn in my 40's. Hopefully they will figure out how to fix this thing for all of us.
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bluethruandthru Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 07:28 PM
Response to Original message
21. Let's never give up!
Today is my beautiful daughter's 20th birthday. She was diagnosed with Type 1 at age 10. I keep thinking how far along we might be if, just two years after her diagnosis, the election of 2000 hadn't been stolen by the Supreme Court and given to the idiot in the white house.
I wonder how immoral he would find stem cell research if he had to watch his children grow up with this terrible disease!
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Left Brain Donating Member (895 posts) Send PM | Profile | Ignore Wed Feb-20-08 09:02 PM
Response to Original message
23. My son was diagnosed Type 1 twenty years ago
when he was just 10 years old. We well know what it's like to play the cruel and difficult Delicate Balance game.

I appreciate that you posted this information. It gives us hope.
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mac2 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 11:49 PM
Response to Reply #23
30. My older sister had Type I Diabeties
and the balance game is a cruel one. The Diabeties pills are giving people side effects so not much progress has been made since the discovery of Insulin.
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caligirl Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 09:51 PM
Response to Original message
25. my son type 1 march 15, 2002 two weeks before his 14th birthday
My son is turning 20 this year. A1C's ranged 5.9-7.3 over the six years he has lived with this awful disease. the good news for us was a successful outcome to the ADA lawsuit with our school district and our state. But he is in a private university and in large part because of the way public schools treated him and us. I had no reason to believe the UC's would have followed ADA laws for college students. I also did not want him in a lecture hall with 600 kids. All is going really well for him now.
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IDemo Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 10:06 PM
Response to Original message
26. Type 1 here, 45 years
As much progress has been made in multiple experiments over the past decade, I feel there will be a cure before another 10 years. Very likely too late for me, but who knows?
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mac2 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-20-08 11:46 PM
Response to Original message
28. Great news for Diabetics
The church and GW Bush outta my way!! We're going to do stem cell research.
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