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Less virulent bird flu cases suggest the danger of pandemic is rising

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steven johnson Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Apr-11-09 07:42 PM
Original message
Less virulent bird flu cases suggest the danger of pandemic is rising
There is a chance that the bird flu is mutating to a less virulent form of the H5N1 form. This is the classic trend of mutation in organisms before they start to become more easily spread in an epidemic and pandemic form. Ironically, the more virulent the organism, the less likely it will be spread.



First the good news: bird flu is becoming less deadly. Now the bad: scientists fear that this is the very thing that could make the virus more able to cause a pandemic that would kill hundreds of millions of people.


This paradox – emerging from Egypt, the most recent epicentre of the disease – threatens to increase the disease's ability to spread from person to person by helping it achieve the crucial mutation in the virus which could turn it into the greatest plague to hit Britain since the Black Death. Last year the Government identified the bird-flu virus, codenamed H5N1, as the biggest threat facing the country – with the potential to kill up to 750,000 Britons.

The World Health Organisation is to back an investigation into a change in the pattern of the disease in Egypt, the most seriously affected country outside Asia. Although infections have been on the rise this year, with three more reported last week, they have almost all been in children under the age of three, while 12 months ago it was mainly adults and older children who were affected. And the infections have been much milder than usual; the disease normally kills more than half of those affected; all of the 11 Egyptians so far infected this year are still alive.

Experts say that these developments make it more likely that the virus will spread. Ironically, its very virulence has provided an important safeguard. It did not get much chance to infect other people when it killed its victims swiftly, but now it has much more of a chance to mutate and be passed on.





New bird flu cases suggest the danger of pandemic is rising

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elocs Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Apr-11-09 07:44 PM
Response to Original message
1. Like the Ebola virus which is actually inefficient because it kills the hosts too quickly
before it can become more widespread.
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Apr-11-09 07:56 PM
Response to Original message
2. The very thing that made H5N1 so deadly
is the very thing that reduced its spread: the infection was confined to the lower respiratory tract instead of the upper, causing a deep pneumonia but not the droplet laden coughing and sneezing that spreads other respiratory infections.

As it attenuates and converts to an upper respiratory form, the next step will be a jump to swine. We're usually next after that unless there's a vaccine.
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TZ Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-12-09 08:28 AM
Response to Reply #2
4. well hopefully that universal flu vaccine
In current trials will pan out...and from I have heard it's looking promising and I do know that it is supposed to confer protection to. H5N1...
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-12-09 12:17 PM
Response to Reply #4
5. I know, I've been following what little has been published on it
It would be wonderful never to get the flu again. The last one damned near killed me.
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phantom power Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-12-09 12:18 AM
Response to Original message
3. Hope it stays out of the sweet spot.
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