Source: NYT
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The latest findings, published this week in The Journal of the American College of Cardiology, indicate that the amount of leisure time spent sitting in front of a screen can have such an overwhelming, seemingly irreparable impact on one’s health that physical activity doesn’t produce much benefit.
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Recreational screen time has an “independent, deleterious relationship” with cardiovascular events and death of all causes, the paper concluded, possibly because it induces metabolic changes.
One possible mechanism, demonstrated in animal studies, is that being sedentary may affect lipid metabolism. Prolonged inactivity appears to sharply reduce the activity of an important enzyme called lipoprotein lipase, which is responsible for breaking down circulating blood lipids and making them available to muscles for energy, Dr. Stamatakis said. Lowered enzyme activity leads to higher levels of fats and triglycerides in the blood, and to a higher risk of cardiovascular disease. Exercise has very little impact on the enzyme’s activity, he said.
Extended sitting may also lead to high levels of low-grade inflammation, which can also lead to heart disease, Dr. Stamatakis said. A marker of low-grade inflammation called C reactive protein was about three times higher in the study participants who spent the most time slouched in front of a screen.
http://well.blogs.nytimes.com/2011/01/12/the-hazards-of-the-couch/