Ketosis is a naturally occurring state. We evolved it for a reason. It is not harmful in non-diabetics. Likewise, ketones are not harmful to non-diabetics. Read on:
Fact vs. Fallacy: Ketosis is DangerousOne reason the Atkins Nutritional Approach has not been part of mainstream thinking (although the tide is beginning to change) has been misinformation. If you've heard that Atkins is dangerous, not to mention ineffective, you may have mixed feelings about starting a lifetime of controlled carbohydrate eating. Once doctors have adequate experience with Atkins, most of them agree that this program should be the treatment of choice not only for obesity but for diabetes and several other diet-related disorders. But sadly, the misinformation has prevented so many people in need from using and benefiting from the best treatment available, ultimately propagating epidemic, life-threatening conditions.
Fallacy: Ketosis is dangerous and causes a variety of medical problems. Fact: Our bodies have only two fuel delivery systems to provide us with energy. Our primary fuel is based on carbohydrate and is delivered as glucose. People who eat three so-called balanced meals every day get virtually all their energy from glucose. But the alternate backup fuel is stored fat, and this fuel system delivers energy by way of ketones whenever our small supply of glucose is used up (in a maximum of two days).
When a person doing Atkins releases ketones, he or she is in ketosis. Ketosis occurs when you are taking in a very low level of carbohydrate from the food you eat, as you will during much of the weight-loss phases of Atkins. Ketones are secreted in the urine (and at times in one's breath), a perfectly normal and natural function of the body. The more ketones you release, the more fat you have dissolved.
Part of this fallacy is the claim that ketones can build up to dangerous levels in the body. Studies show that ketone bodies are very tightly regulated in the body and will not increase beyond the normal range in healthy individuals. (Uncontrolled diabetics, alcoholics and people who have been on prolonged fasts might see an increase in ketones beyond the normal range.) The body regulates ketone levels the same way it regulates blood-glucose or pH levels1-4. And Dr. Atkins' medical practice repeatedly observed that overweight patients produce just enough ketones to meet their immediate needs for fuel—and no more. A person will have no more ketones after three months of controlling carbohydrates than they do after three days. It is highly unlikely that people, other than insulin-dependent diabetics, will build up ketones.
Confusion about ketosis often
comes from people mistaking it for ketoacidosis, a condition found in Type I diabetics; this occurs when a person's blood sugar is out of control and he or she cannot produce insulin. No doctor should have trouble differentiating physiologic ketosis, which you will experience while doing Atkins, from ketoacidosis. Further, since people are often overweight specifically because of an overabundance of insulin, it is essentially impossible for them to be in ketoacidosis.
Some individuals at the ketogenic level of controlled carbohydrate eating may experience mild symptoms such as unusual breath odor and constipation. However, the vast majority of individuals do not develop problems. One study of a severely ketogenic diet showed that ketosis was benign, with no complications or side effects when studied in metabolic ward conditions. The month-long study documented heart, kidney, liver and blood-cell functions in the patients and found no adverse effects.
In other studies, it has been shown that bone health was not compromised and that renal (kidney) function was found to be stable on controlled carbohydrate diets. There is even scientific literature on hyperlipidemia (elevated blood fats, such as cholesterol and triglycerides), showing improved values on controlled carbohydrate diets.
Though the article is unabashedly pro-Atkins, it has has some decent references. As someone who has been a low-carber for 35 years and has read everything I could about low-carb diets, the above sums up my position. You and I often agree, tom_paine, but on this one you're wrong.