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Guardian: "Drugs firm blocks cheap blindness cure"

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mrfrapp Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Jun-18-06 05:34 AM
Original message
Guardian: "Drugs firm blocks cheap blindness cure"
A major drug company is blocking access to a medicine that is cheaply and effectively saving thousands of people from going blind because it wants to launch a more expensive product on the market.

Ophthalmologists around the world, on their own initiative, are injecting tiny quantities of a colon cancer drug called Avastin into the eyes of patients with wet macular degeneration, a common condition of older age that can lead to severely impaired eyesight and blindness. They report remarkable success at very low cost because one phial can be split and used for dozens of patients.

[...]

Avastin was first used on human eyes by Philip Rosenfeld, an ophthalmologist in the US, who was aware of animal studies carried out by Genentech that showed potential in eye conditions. This unlicensed use of Avastin has spread across continents entirely by word of mouth from one doctor to another. It has now been injected into 7,000 eyes, with considerable success.

[...]

Prof Rosenfeld said the real issue was drug company profits. "This truly is a wonder drug," he said. "This shows both how good they are and on the flip side, how greedy they are." He would like to see governments fund clinical trials of drugs such as Avastin in the public interest.

[...]

http://www.guardian.co.uk/medicine/story/0,,1799772,00.html

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rodeodance Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Jun-18-06 06:03 AM
Response to Original message
1. It is wrong to say it is unlicensed (for eye use)--I is not approved by

some experts. Yet, many drugs are developed for one use and eventually get used for other uses.

........This unlicensed use of Avastin has spread across continents entirely by word of mouth from one doctor to another. It has now been injected into 7,000 eyes, with considerable success.
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megatherium Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Jun-19-06 12:42 AM
Response to Reply #1
3. off label use of drugs is common and legal.
but insurance companies might not pay for such use.
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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Jun-18-06 06:08 AM
Response to Original message
2. For those who cannot get it..... for those who may need it....
http://www.lef.org/protocols/prtcl-071.shtml



* Lutein Plus with lutein, zeaxanthin is suggested at a dosage of 1 tbsp daily with a fatty meal
* Super Zeaxanthin with Lutein; 5 mg of zeaxanthin and 10 mg of lutein per capsule, 1 or 2 capsules daily
* Life Extension’s Solarshield sunglasses
* Lipoic acid, 150-300 mg per day
* Selenium, 200-300 mcg per day
* Riboflavin, 50-150 mg per day
* Taurine is suggested at a daily dosage of 1,000 mg
* Coenzyme Q10 – 100 to 300 mg per day
* Life Extension Mix, 9 tablets, 14 capsules, or 3 scoops per day in divided doses
* Life Extension Booster, suggested dosage of 1 capsule daily
* Brite Eyes II eye drops (N-acetyl-carnosine) is suggested at 1-2 drops in each eye daily
* Super EPA/DHA with Sesame Lignans, two soft gels daily (for the dry and wet types).
* Ginkgo biloba extract, 120 mg per day.
* Grape seed-skin extract, 200-300 mg per day
* Bilberry extract, 150 mg per day
* Super Absorbable Soy Isoflavones for genistein: 1 capsule twice per day.
* Hydergine, 4-5 mg per day (prescription only)

The Age-Related Eye Disease Study (AREDS) recommended recipe consists of the following dosages:

* Vitamin A (Beta Carotene), 25,000 IU daily
* Vitamin C, 500 mg daily
* Vitamin E, 400 mg daily
* Zinc, 80 mg daily
* Copper, 2 mg daily
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