SSRIs Given During Pregnancy May Cause Withdrawal Symptoms in the Neonate

[HuckleB]

SSRIs Given During Pregnancy May Cause Withdrawal Symptoms in the Neonate

http://www.medscape.com/viewarticle/498763

"Selective serotonin reuptake inhibitors (SSRIs) given during pregnancy may lead to withdrawal symptoms in the neonate, according to the results of a database analysis published in the Feb. 5 issue of The Lancet.

"SSRIs have been associated with withdrawal symptoms," write Emilio J. Sanz, from the University of La Laguna in Spain, and colleagues. "Neonatal withdrawal syndrome associated with SSRIs — characterised by convulsions, irritability, abnormal crying, and tremor — has been reported in several cases."

Using the data mining method routinely used to screen the World Health Organization database of adverse drug reactions, the investigators identified an association between paroxetine and neonatal convulsions in December 2001. They then used an information component (IC) measure to screen for unexpected adverse reactions relative to information contained in the database, and they evaluated cases of neonatal convulsions and neonatal withdrawal syndrome associated with drugs included in the anatomical therapeutic chemical groups N06AB and N06AX.

..."

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Other links with longer write-ups on this story:

Anti-depressants pregnancy risk
http://news.bbc.co.uk/1/hi/health/4229851.stm

Antidepressants Linked to Withdrawals in Newborns, Study Says
http://www.bloomberg.com/apps/news?pid=10000103&sid=aaWQez5K8H1g&refer=us

Newborns at Risk of Antidepressant Withdrawal, Study Says
http://www.washingtonpost.com/wp-dyn/articles/A63188-2005Feb4.html

[yurbud]

1. this was known and told to patients from the beginning

[PunkPop]

2. Wow. What great timing.

My wife found out she was pregnant two weeks ago. Stopped taking Zoloft immediately. She will find these articles very interesting. Thanks.

[ynksnewyork2]

4. Congratulations to you and your wife!

[PunkPop]

5. Thanks!

[ynksnewyork2]

3. not new

The OB's I work with have known this for a few years now and have been counseling woman during prenatal care. I'm not sure why it's out now, it's old news.

[HuckleB]

6. Noting something in clinic and actual research are two different things.

And clinical observation and research often disagree with one another.

[KissMeKate]

7. The more we know about anti depressants

the more dangerous they sound- and we cant even say for sure that they even work!