Reply #75: This is a long process [View All]

[mrs_p]

Probably involves making plasmids for each influenza gene, performing reverse genetics, then site directed mutagenesis All that before passing in live animals. Any flu lab could already do this if they wanted and had all the protocols and viruses in place. This is not something you could do in your garage as it takes special skill and obtaining the isolates from established labs that don't just collaborate with anyone.

I haven't read this particular paper, but these types of studies are done to determine how influenza jumps the species barrier. It is actually pretty important for protecting human health.

FWIW: The focus of my PhD is influenza viruses....