One Thing Leads to Another

[NNadir]

23. Interesting. I did a quick search on Google Scholar for publications since 2019...

...and called up this paper: Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial (Lancet Neurology, Volume 18, Issue 6, June 2019, Pages 549-558)

...which is about a phase 1B (safety) trial of a potential treatment, which describes the symptoms as these:

Progressive supranuclear palsy is a neurodegenerative disease that causes impairments in physical function, including gait, postural stability (resulting in falls), speech, and swallowing, as well as in cognition and behaviour, such as apathy and frontal dementia.1 Individuals with the classic form of the disease, progressive supranuclear palsyRichardson syndrome, have progressive ocular motor impairments and frequent falls. Progressive supranuclear palsy imparts a substantial caregiver and economic burden; individuals with the neurodegenerative disease require a wide range of services, many of which are provided by unpaid caregivers (ie, family and friends).2 Currently, no disease-modifying therapies for progressive supranuclear palsy exist.1 Present therapeutic approaches, including levodopa, are palliative and generally provide only transient symptomatic benefit.1 Inevitably, progressive supranuclear palsy is fatal, and death occurs a median of 7·3 years after symptom onset.1,3

I haven't heard anything about frequent falls, but if it is the case that he has this disease - I'm in no way competent to judge - the good news is that he's likely die sooner rather than later.