Oxford scientists say a vaccine may be widely available by September

[C Moon]

Source: CBS Evening News

In the global race to find a vaccine, Oxford University just jumped way ahead of the pack. Human testing is already underway, and scientists say they're hopeful a coronavirus vaccine will be widely available by September.

Technology the lab had already developed in previous work on inoculations for other viruses, including a close relative of COVID-19, gave it a head start.

"Well personally, I have a high degree of confidence about this vaccine, because it's technology that I've used before," said Sarah Gilbert, a professor of vaccinology at the university.

Read more: https://www.cbsnews.com/news/oxford-university-vaccine-scientists-say-coronavirus-vaccine-widely-available-by-september-covid-19/

[bronxiteforever]

1. Kick and recommend.

Fingers crossed.

[redstatebluegirl]

2. Be careful, scientists are all trying to be "first".

It seems really premature to me.

[Jarqui]

3. +1,000

[FarPoint]

7. You are correct...

[cstanleytech]

4. I'll probably pass if they rush it that fast.

[Bernardo de La Paz]

9. You don't have to be first or last. . . . nt

[Hoyt]

5. Unfortunately, there are trump type con people even among scientists.

Hope I’m wrong.

[caraher]

12. True. But this is Oxford...

Oxford's reputation isn't a fluke, so while it's a fast timeline I doubt it's a scam.

I saw an interview with an American researcher whose virus vaccine work lost its funding under Trump, and the impression I got from that was that he felt his group would have been well-positioned to develop a novel coronavirus vaccine quickly had his lab not been gutted. So it doesn't seem implausible that Oxford might have a group who could develop something quickly.

I think the biggest problem with September availability might be whether doing so would involve taking too many shortcuts with clinical trials for safety and efficacy.

[Hoyt]

15. They do have credentials and experience with similar vaccines.

If developed that quickly, I’d probably be more concerned whether it’s effective than would it cause some fatal reaction, birth defects, or similar.

But, glad folks are working on vaccines and treatments.

[Bernardo de La Paz]

14. You are almost certainly wrong in this case. If vaccine fails, more likely to unknowns than incompet

The vaccine could fail for 3 reasons:

1) Scammer. Highly unlikely. Good reputations involved: university, professor, drug maker.

2) Incompetence: Highly unlikely. See #1.

3) Too many unknowns: Distinctly possible. The virus has surprised science multiple times so far. Even so, I think it is likely to work. But it won't be in time to save tRump.

And September could easily become October or November.

I'm thinking that if this one doesn't work well enough or safely enough, there will be another few hot on their heels with at least one among them that does work well and safely.

[Hoyt]

20. Yeah, right. You obviously weren't paying attention during early years of HIV.

Plus, we’ll know soon enough if they have a vaccine for millions by September, October, November.

If not, the doc jumped the gun.

[Bernardo de La Paz]

25. Oh, come on, I was paying attention. 2013 was not early years, but I did have to look it up.

0) HIV is unique. Covid-19 much less so, though it does have unique features.

1) That researcher at Iowa State is not the same stature. Assistant prof only.

2) Sorry, but Iowa State is not the university Oxford is.

3) That wasn't even animal trials. It was in vitro research that was fraudulent. Oxford is already beyond in vitro and beyond animal trials.

4) Multiple levels of review and signoff to get to human trials and to convince large drug manufacturer to ramp up production this early.

5) An Israeli team is already in human trials too.

6) Anything is possible, but I put your hypothesis in the extremely unlikely category for multiple reasons.

[Bernardo de La Paz]

29. 90 and 6

Link to tweet

Nature
@nature
More than 90 vaccines are being developed against SARS-CoV-2 across the world. At least six groups have begun injecting formulations into volunteers in safety trials. Here is a graphical guide explaining each vaccine design.

They can't all be frauds.

[Hoyt]

37. September, 5 months away?

[Bernardo de La Paz]

42. 4 and a bit to First, 5 and a bit to end of Sept. Usually takes 12-18 months to develop a vaccine

12 months from Feb 1 = Feb 1, 2021.
2021-02-01
7 months from Feb 1 = Sep 1, 2020.
2020-09-01

Yes it is "breakneck speed".

[Hoyt]

46. Plus production.

[mwooldri]

30. Not in this case.

We're talking about the University of Oxford. Also an institute that has been working on vaccines for years, though the Jenner Institute has only been around in its present form since 2005. They have managed to make a giant leap purely because they were working on a vaccine for a similar virus to Covid-19 and we're pretty advanced with that research.

Plus it's not a pharmaceutical company but a research institute funded by grants from a lot of interested bodies - the UK and US health Institutes, Bill and Melinda Gates foundation, Wellcome Trust, and others.

My hope is that these guys are successful, and don't get screwed over by Big Pharma. They seem to be pretty confident since they got a contract with a manufacturer in India for a million doses of the stuff.

[Hoyt]

39. Hope they do. But scientists can be overly exuberant too.

Gates sure hasn’t been talking September in recent interviews. I do trust him, but not September or even late fall.

[AlexSFCA]

41. more importantly, they are not dependent on FDA approval to start mass production

the cost of the vaccine in terms of economic value is probably in tens of trillions.

[guillaumeb]

6. Trump will claim credit for this. eom

[Shermann]

10. Not if it comes from Team WHO

Then he'll have some 'splaining to do

[cstanleytech]

47. I wonder if he will claim responsibility for those that got sick and those that died due to

his and the Republicans negligence as well?

[guillaumeb]

51. Trump takes credit always, responsibility never. eom

[stillcool]

8. science is like a foreign language to me...

but I'm glad I don't live in India.

Wasting no time, the largest drugmaker in the world, based in India, will start producing millions of the Oxford vaccines by next month, even before they've been proven to work.

[brewens]

11. I we all got vaccinated in time the the big celebration in November would be good. n/t

[dem4decades]

13. Most experts are still saying 18 months, that a big difference.

Not getting my hopes up but would gladly be wrong.

[not fooled]

16. OK for the rest of the world

but what about the US? Gotta tack on however long it takes jughead and his pa in law to figure out how to rip off the nation in order to access the vaccine. Although if orange anus thinks it will help his re-election they will fast track it.

[sakabatou]

17. Here's hoping

[Rebl2]

18. Believe it

when I see it. Just not convinced.

[iluvtennis]

19. It works on monkeys. Scientists now moving to trials with humans. Fingers crossed.

In the human trials, 550 participants are given the vaccine, and another 550 receive a placebo.

[nitpicker]

21. Issues include

1. Just because there has been work done studying a close relative of this CV, it doesn't mean they have a way to deal with this CV. Think of how many flu strains go into a vaccine- and sometimes they miss the one that becomes prevalent (e.g A versus B), or a new version pops up such as 2009 H1N1.

2.. IF they find a magic bullet (effective),

3. Are there enough supplies to quickly provide enough vaccine?

[mwooldri]

32. For #3 US manufacturing may be a problem.

Big Pharma likes "exclusive" licenses to manufacture a drug. Jenner Institute isn't big pharma but a grant funded research laboratory. Given the scale of the need, I hope the Big Pharma companies will step up and make the stuff. Otherwise we'll be waiting on India and Israel through the generic manufacturers to make the vaccine. They seem to be positive about the vaccine since they're making a million doses already.

[gab13by13]

40. #1 is the kicker,

the study was done on a similar virus from what I heard, I could be wrong.

We could get a vaccine by September, September 2021. I don't want a shot in September 2020.

[Fiendish Thingy]

22. To be widely available by September, they'd have to have a proven effective vaccine...now.

And they don’t. If flu vaccines are selected in January for mass production for the following October, how in the hell are they going to have a COVID vaccine “widely available” before the seasonal flu shot is available.

Wonderful if it’s true, but I am sceptical.

[BrightKnight]

52. I think they are manufacturing before approval

and running animal trials while running human trials. I thought I heard that the UK manufacturing facility was still being built. IDK

I hope the rest of the world is not expecting anything from the Trump administration.

[Sancho]

23. Too bad that TP45 said fuck the WHO and won't share with other countries...

[iluvtennis]

24. Bill and Melinda Gates foundation is funding this Oxford effort as well as others

https://www.seattletimes.com/nation-world/in-race-for-a-coronavirus-vaccine-an-oxford-group-leaps-ahead/

In race for a coronavirus vaccine, an Oxford group leaps ahead

In the worldwide race for a vaccine to stop the coronavirus, the laboratory sprinting fastest is at Oxford University.

Most other teams have had to start with small clinical trials of a few hundred participants to demonstrate safety. But scientists at the university’s Jenner Institute had a head start on a vaccine, having proved in previous trials that similar inoculations — including one last year against an earlier coronavirus — were harmless to humans.

That has enabled them to leap ahead and schedule tests of their new coronavirus vaccine involving more than 6,000 people by the end of next month, hoping to show not only that it is safe but also that it works.

The Oxford scientists now say that with an emergency approval from regulators, the first few million doses of their vaccine could be available by September — at least several months ahead of any of the other announced efforts — if it proves to be effective.

Now, they have received promising news suggesting that it might.

Scientists at the National Institutes of Health’s Rocky Mountain Laboratory in Montana last month inoculated six rhesus macaque monkeys with single doses of the Oxford vaccine. The animals were then exposed to heavy quantities of the virus that is causing the pandemic — exposure that had consistently sickened other monkeys in the lab. But more than 28 days later all six were healthy, said Vincent Munster, the researcher who conducted the test.

...read more at link

[Thekaspervote]

26. Oxford is impeccable in science and research. highly unlikely they are just talking thru their hat

And if Bill and Melinda Gates Foundation is behind it....it’s a winner

[Steelrolled]

27. I find it interesting how much skepticism there is about this info, even

when it comes from a prominent researcher with practical experience. I'm skeptical as well, there are just too many "experts" trying to make headlines.

[Thekaspervote]

28. As a professional person of science... headlines aren't what drive us

[Steelrolled]

36. People come in many flavors.

[Thekaspervote]

44. For true scientists, the kind lucky enough to work at Oxford..there's only one goal..discovery

[a la izquierda]

50. As an expert in a different field (history)

I find the disdain of experts in this country to be exhausting quite frankly.

[mopinko]

31. the thing is that this is already well down the pipeline.

already had safety testing, and already has show efficacy in monkeys.
the path from here is short. the next hurdle is production.

[Thekaspervote]

34. Under the DPA lrg pharma could be ordered to produce the vaccine here in the US

It’s not like Oxford is going to patent it. They will make their vaccine formula available to all. Their take is Oxford did it!

[Grokenstein]

33. Donny's response:

"We don't want your stupid commie vaccine, it causes autism. Every American citizen will receive my hydroclorophyllicsomething, for a very reasonable charge, which absolutely will not be a monthly charge taken directly out of your paycheck or benefits if you're a goddamn taker. No, China will pay for it!"

[Thekaspervote]

35. That may be dotard's response, but as we have seen the real nuts and bolts of running the

Country during a pandemic has been taken up by state and local governments. I doubt this will be any different

[C Moon]

48. Yes. Governors, mayors, etc have been doing amazing things in the face of that evil traitor.

[DesertRat]

38. "if it proves to be effective"

Fingers crossed!

[captain queeg]

43. Well, let's hope

I think we’ve all because pretty suspicious & cautious. It may or may not work out but I’m rooting for them.

[captain queeg]

45. If it does prove promising Jarad and T-wreck will try to get control of it somehow

Or at least take credit for it. Of course if it shows any promise tRump will start talking it up and jinx it.

I’m waiting for him to start suggesting nicotine patches.

[C Moon]

53. He will, but he has to buy shares in a nicotine patch company, first.

[GoneOffShore]

49. I'm going to be cautiously optimistic on this.

Oxford has always been a great place for research and discovery.